Title : 3-deazaadenosine, a S-adenosylhomocysteine hydrolase inhibitor, has dual effects on NF-kappaB regulation. Inhibition of NF-kappaB transcriptional activity and promotion of IkappaBalpha degradation.

Pub. Date : 1999 Jul 2

PMID : 10383397






1 Functional Relationships(s)
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1 The reduction of IkappaBalpha by DZA is neither involved in IkappaB kinase complex activation nor modulated by the addition of homocysteine. 3-deazaadenosine nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Mus musculus