Title : Metabolism-dependent hepatotoxicity of methimazole in mice depleted of glutathione.

Pub. Date : 1999 May-Jun

PMID : 10362270






1 Functional Relationships(s)
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1 Pretreatment with hepatic cytochrome P-450 monooxygenase inhibitors--cobalt chloride, isosafrole, methoxsalen, metyrapone and piperonyl butoxide-prevented or tended to suppress the hepatotoxicity induced by MMI in combination with BSO. Methoxsalen cytochrome P450, family 20, subfamily a, polypeptide 1 Mus musculus