Title : CD94/NKG2-A inhibitory complex blocks CD16-triggered Syk and extracellular regulated kinase activation, leading to cytotoxic function of human NK cells.

Pub. Date : 1999 Jun 15

PMID : 10358164






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both tyrosine phosphorylation and activation of Syk kinase together with tyrosine phosphorylation of CD16 receptor zeta subunit are markedly inhibited by the coengagement of CD94/NKG2-A complex. Tyrosine killer cell lectin like receptor D1 Homo sapiens
2 Both tyrosine phosphorylation and activation of Syk kinase together with tyrosine phosphorylation of CD16 receptor zeta subunit are markedly inhibited by the coengagement of CD94/NKG2-A complex. Tyrosine killer cell lectin like receptor D1 Homo sapiens