Title : Thalidomide up-regulates prostate-specific antigen secretion from LNCaP cells.

Pub. Date : 1999

PMID : 10357564






4 Functional Relationships(s)
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1 Comparison of cDNA expression arrays hybridized with thalidomide-treated LNCaP cDNA probes suggests that thalidomide may up- or downregulate expression of angiogenesis-related genes, i.e., vitronectin, but these differential effects require further verification. Thalidomide vitronectin Homo sapiens
2 Furthermore, preliminary data from cDNA nucleic acid arrays of thalidomide-treated LNCaP cells suggest that thalidomide upregulates a potential angiogenic modulatory protein, the vitronectin precursor, which may eventually link thalidomide"s antiangiogenic activity with modulation of angiogenic vascular integrin pathways. Thalidomide vitronectin Homo sapiens
3 Furthermore, preliminary data from cDNA nucleic acid arrays of thalidomide-treated LNCaP cells suggest that thalidomide upregulates a potential angiogenic modulatory protein, the vitronectin precursor, which may eventually link thalidomide"s antiangiogenic activity with modulation of angiogenic vascular integrin pathways. Thalidomide vitronectin Homo sapiens
4 Furthermore, preliminary data from cDNA nucleic acid arrays of thalidomide-treated LNCaP cells suggest that thalidomide upregulates a potential angiogenic modulatory protein, the vitronectin precursor, which may eventually link thalidomide"s antiangiogenic activity with modulation of angiogenic vascular integrin pathways. Thalidomide vitronectin Homo sapiens