Title : The role of SHIP in growth factor induced signalling.

Pub. Date : 1999

PMID : 10354708






1 Functional Relationships(s)
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1 The recently cloned, hemopoietic-specific, src homology 2 (SH2)-containing inositol phosphatase, SHIP, is rapidly gaining prominence as a potential regulator of all phosphatidylinositol (PI)-3 kinase mediated events since it has been shown both in vitro and in vivo to hydrolyze the 5" phosphate from phosphatidylinositol-3,4,5-trisphosphate (PI-3,4,5-P3). phosphatidylinositol 3,4,5-triphosphate inositol polyphosphate-5-phosphatase D Mus musculus