Title : Regulation of type 3 iodothyronine deiodinase expression in cultured rat astrocytes: role of the Erk cascade.

Pub. Date : 1999 Jun

PMID : 10342885






3 Functional Relationships(s)
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1 D3 induction by TPA was blocked by GF 109203X, an inhibitor of protein kinase C. In addition, the effects of TPA and bFGF were partially prevented by PD 98059, a specific inhibitor of MEK and the Erk signaling cascade. Tetradecanoylphorbol Acetate Eph receptor B1 Rattus norvegicus
2 D3 induction by TPA was blocked by GF 109203X, an inhibitor of protein kinase C. In addition, the effects of TPA and bFGF were partially prevented by PD 98059, a specific inhibitor of MEK and the Erk signaling cascade. Tetradecanoylphorbol Acetate Eph receptor B1 Rattus norvegicus
3 In addition, the stimulatory effects of TPA and bFGF on D3 mRNA and activity appear to be mediated at least in part by activation of the MEK/Erk signaling cascade. Tetradecanoylphorbol Acetate Eph receptor B1 Rattus norvegicus