Pub. Date : 1999 Jun 1
PMID : 10332086
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Coexpression of RGS2, 5 and 8 accelerates the speed for ACh-mediated activation and deactivation of GIRK1/2 and GIRK1/4 currents. | Acetylcholine | potassium inwardly rectifying channel subfamily J member 3 L homeolog | Xenopus laevis |
| 2 | Coexpression of RGS2, 5 and 8 accelerates the speed for ACh-mediated activation and deactivation of GIRK1/2 and GIRK1/4 currents. | Acetylcholine | potassium inwardly rectifying channel subfamily J member 3 L homeolog | Xenopus laevis |
| 3 | Bordetella pertussis toxin completely abolished ACh-mediated current amplification of GIRK channels coexpressed with or without RGS2. | Acetylcholine | potassium inwardly rectifying channel subfamily J member 3 L homeolog | Xenopus laevis |
| 4 | Two single point mutations in the RGS2 protein (RGS2(N109S) and RGS2(L180F)) reduced the acceleration of current amplification after ACh application on GIRK1/4 channels compared with RGS2 wild-type protein. | Acetylcholine | potassium inwardly rectifying channel subfamily J member 3 L homeolog | Xenopus laevis |