Title : Expression of IL-17 in human memory CD45RO+ T lymphocytes and its regulation by protein kinase A pathway.

Pub. Date : 1999 Apr

PMID : 10328864






2 Functional Relationships(s)
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1 IL-17 and interferon gamma(IFN-gamma) mRNA were both inhibited in the presence of PGE2 or the cAMP analogue (dibutyryl-cAMP), while the anti-inflammatory cytokine IL-10 was highly increased. Dinoprostone interleukin 17A Homo sapiens
2 However, we suggest that PGE2 may be more efficient in blocking both IL-17 and IFN-gamma expression in already primed memory T cells, rather than in suppressing naive T cells that could represent a significant source of IL-10. Dinoprostone interleukin 17A Homo sapiens