Title : Design and synthesis of sulfonyl-substituted 4,5-diarylthiazoles as selective cyclooxygenase-2 inhibitors.

Pub. Date : 1999 Apr 19

PMID : 10328306






1 Functional Relationships(s)
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1 A series of novel sulfone substituted 4,5-diarylthiazoles have been synthesized and evaluated for their inhibition of the two isoforms of human cyclooxygenase (COX-1 and COX-2). Sulfones mitochondrially encoded cytochrome c oxidase II Homo sapiens