Title : Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells.

Pub. Date : 1999 May 15

PMID : 10229667






1 Functional Relationships(s)
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1 The simultaneous addition of recombinant human GM-CSF (rhGM-CSF) to M-07e cultures delayed the activation of caspase 3 and Bcl-2 cleavage triggered by Z-LLL-CHO, suggesting that the activation of the GM-CSF signalling pathway can partly overcome the apoptotic effect induced by Z-LLL-CHO. benzyloxycarbonylleucyl-leucyl-leucine aldehyde caspase 3 Homo sapiens