Title : Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.

Pub. Date : 1999 Mar

PMID : 10219979






1 Functional Relationships(s)
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1 The 5-HT2C receptor agonists, mCPP and MK 212, fully generalized to Ro 60-0175 with ED50s of 0.8 and 0.4 mg/kg, s.c., respectively, whereas the preferential 5-HT2B agonist, BW 723C86 ( > 10.0 mg/kg, s.c.) and the 5-HT2A agonist, DOI ( > 2.5 mg/kg, s.c.), were ineffective. 1-(3-chlorophenyl)piperazine 5-hydroxytryptamine receptor 2B Rattus norvegicus