Title : Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells.

Pub. Date : 1999 Apr

PMID : 10206278






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The caspase I selective protease inhibitor, YVAD-cmk, inhibited internucleosomal DNA fragmentation and PAI-2 cleavage of okadaic acid and camptothecin-induced apoptotic cells. YVAD C-X-C motif chemokine ligand 9 Homo sapiens
2 YVAD-cmk rather sensitively and non-toxically inhibited camptothecin-induced morphology, but not okadaic acid-induced morphology. YVAD C-X-C motif chemokine ligand 9 Homo sapiens