Title : Matrix degradation by chondrocytes cultured in alginate: IL-1 beta induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation.

Pub. Date : 1998 Sep

PMID : 10197168






4 Functional Relationships(s)
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Protein Name
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1 RESULTS: IL-1 beta induced a profound GAG release (approximately 80% after 2 days at 20 ng/ml IL-1 beta) that was both time and IL-1 beta concentration dependent. Glycosaminoglycans interleukin 1 beta Homo sapiens
2 RESULTS: IL-1 beta induced a profound GAG release (approximately 80% after 2 days at 20 ng/ml IL-1 beta) that was both time and IL-1 beta concentration dependent. Glycosaminoglycans interleukin 1 beta Homo sapiens
3 RESULTS: IL-1 beta induced a profound GAG release (approximately 80% after 2 days at 20 ng/ml IL-1 beta) that was both time and IL-1 beta concentration dependent. Glycosaminoglycans interleukin 1 beta Homo sapiens
4 In the presence of APMA, GAG release from IL-1 beta treated beads was significantly increased from 24 to 31%. Glycosaminoglycans interleukin 1 beta Homo sapiens