Title : Selective inhibition of eukaryote protein kinases by anti-inflammatory triterpenoids.

Pub. Date : 1999 Feb

PMID : 10083838






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 alpha-Amyrin inhibits plant Ca(2+)-dependent protein kinase (CDPK) (IC50 52 microM) but lupeol and the triterpenoid esters tested are ineffective. beta-amyrin calcium-dependent protein kinase Solanum tuberosum
2 alpha-Amyrin also inhibits CDPK competitively and alpha-amyrin, lupeol and lupeol linoleate are competitive inhibitors of PKC. beta-amyrin calcium-dependent protein kinase Solanum tuberosum