Title : Kinetic parameters and tissue distribution of 5-oxo-L-prolinase determined by a fluorimetric assay.

Pub. Date : 1999 Jan 13

PMID : 10078874






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 5-Oxo-L-prolinase (5-OPase) catalyses the hydrolysis of 5-oxo-L-proline to glutamate with concomitant stoichiometric cleavage of ATP to ADP, a reaction which is known to be part of the gamma-glutamyl cycle-an interrelated series of reactions involved in the synthesis and metabolism of glutathione. Pyrrolidonecarboxylic Acid 5-oxoprolinase, ATP-hydrolysing Homo sapiens
2 5-Oxo-L-prolinase (5-OPase) catalyses the hydrolysis of 5-oxo-L-proline to glutamate with concomitant stoichiometric cleavage of ATP to ADP, a reaction which is known to be part of the gamma-glutamyl cycle-an interrelated series of reactions involved in the synthesis and metabolism of glutathione. Pyrrolidonecarboxylic Acid 5-oxoprolinase, ATP-hydrolysing Homo sapiens
3 Thus, the degradation of 5-oxo-L-proline by 5-OPase leads to the downregulation of this stimulus. Pyrrolidonecarboxylic Acid 5-oxoprolinase, ATP-hydrolysing Homo sapiens