Title : Structural basis for the inhibitory effect of brefeldin A on guanine nucleotide-exchange proteins for ADP-ribosylation factors.

Pub. Date : 1999 Mar 16

PMID : 10077583






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 All known ARF guanine nucleotide-exchange proteins contain a Sec7 domain of approximately 200 amino acids that includes the active site and fall into two classes that differ in molecular size and susceptibility to inhibition by the fungal metabolite brefeldin A (BFA). Guanine Nucleotides cytohesin 1 Homo sapiens