Title : Stress and self-injurious behavior; hormonal and serotonergic parameters in mentally retarded subjects.

Pub. Date : 1999 Jan

PMID : 10071178






1 Functional Relationships(s)
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1 In mentally retarded subjects, several hypotheses have been formulated concerning the pathogenesis of SIB, particularly about the involvement of serotonin and beta-endorphin, which are supported by beneficial treatment effects of the opiate antagonist naltrexone and serotonin modulating compounds, respectively. Naltrexone proopiomelanocortin Homo sapiens