Title : Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidation.

Pub. Date : 1999 Feb

PMID : 10051052






1 Functional Relationships(s)
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1 This finding was accompanied by a corresponding reduction of the inactive glucuronide metabolite of MPA (MPAG) in patients, suggesting that tacrolimus may effect the conversion of MPA to MPAG by the enzyme UDP-glucuronosyltransferase (UDPGT). Glucuronides UDP glucuronosyltransferase family 1 member A4 Homo sapiens