Pub. Date : 1999 Feb
PMID : 10048600
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A correlation study using a panel of human liver microsomes showed that the formation of 9-hydroxyrisperidone is highly correlated with CYP2D6 and 3A activities. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | This observation is confirmed by the findings that both quinidine (inhibitor of CYP2D6) and ketoconazole (inhibitor of CYP3A4) can inhibit the formation of 9-hydroxyrisperidone. | Paliperidone Palmitate | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |