Title : Modulation of the channel activity of the epsilon2/zeta1-subtype N-methyl D-aspartate receptor by PSD-95.

Pub. Date : 1999 Mar 5

PMID : 10037761






2 Functional Relationships(s)
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1 Expression of PSD-95 decreased the sensitivity of the NMDA receptor channels to L-glutamate. Glutamic Acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis
2 Mutational studies showed that the interaction between the COOH terminus of the epsilon2 subunit of the NMDA receptor and the second PSD-95/Dlg/Z0-1 domain of PSD-95 is critical for the decrease in glutamate sensitivity. Glutamic Acid glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis