Title : Discordant effects of rapamycin on proliferation and p70S6 kinase phosphorylation in normal and neoplastic rat chromaffin cells.

Pub. Date : 1999 Jan 15

PMID : 10025577






1 Functional Relationships(s)
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1 PC12 cells are refractory to the antiproliferative effect of rapamycin, although rapamycin does exert its expected inhibitory effect in PC12 cells on both basal and NGF-stimulated activation of one of its biochemical targets, the 70-kDa S6 protein kinase (p70S6K). Sirolimus ribosomal protein S6 kinase B1 Rattus norvegicus