Cisplatin

tumor protein p53 ; Homo sapiens







886 Article(s)
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51 31897925 Management of sinonasal adenocarcinomas with anterior skull base extension. 2020 Dec 1
52 31898732 Cooperation of SRPK2, Numb and p53 in the malignant biology and chemosensitivity of colorectal cancer. 2020 Jan 31 1
53 31935430 GATA3 as a master regulator for interactions of tumor-associated macrophages with high-grade serous ovarian carcinoma. 2020 Apr 1
54 32044796 Anti-prostate cancer activity of a nanoformulation of the spleen tyrosine kinase (SYK) inhibitor C61. 2020 Jul 1
55 32052927 LncRNA MST1P2/miR-133b axis affects the chemoresistance of bladder cancer to cisplatin-based therapy via Sirt1/p53 signaling. 2020 Apr 1
56 32063580 Cisplatin in Combination with MDM2 Inhibition Downregulates Rad51 Recombinase in a Bimodal Manner to Inhibit Homologous Recombination and Augment Tumor Cell Kill. 2020 Apr 2
57 32088177 Bisdemethoxycurcumin attenuates cisplatin-induced renal injury through anti-apoptosis, anti-oxidant and anti-inflammatory. 2020 May 5 2
58 32122297 Sirt2-associated transcriptome modifications in cisplatin-induced neuronal injury. 2020 Mar 2 1
59 32135156 Influence of nonprotective autophagy and the autophagic switch on sensitivity to cisplatin in non-small cell lung cancer cells. 2020 May 3
60 32152233 PIK3CA and p53 Mutations Promote 4NQO-Initated Head and Neck Tumor Progression and Metastasis in Mice. 2020 Jun 1
61 32211658 Cisplatin binds to the MDM2 RING finger domain and inhibits the ubiquitination activity. 2020 Apr 28 2
62 32217375 Bromocoumarinplatin, targeting simultaneously mitochondria and nuclei with p53 apoptosis pathway to overcome cisplatin resistance. 2020 Jun 3
63 32237195 Preclinical Anticancer Activity of an Electron-Deficient Organoruthenium(II) Complex. 2020 Jun 4 2
64 32238696 Pro-apoptotic functions of TRAF2 in p53-mediated apoptosis induced by cisplatin. 2020 3
65 32355541 Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells. 2020 2
66 32368398 Cisplatin sensitivity mediated by NKX2-1 in lung adenocarcinoma is dependent on p53 mutational status via modulating TNFSF10 expression. 2020 2
67 32382008 The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53. 2020 May 7 2
68 32466567 Activation of Mitochondrial 2-Oxoglutarate Dehydrogenase by Cocarboxylase in Human Lung Adenocarcinoma Cells A549 Is p53/p21-Dependent and Impairs Cellular Redox State, Mimicking the Cisplatin Action. 2020 May 26 1
69 32468080 Protein expression profiling identifies differential modulation of homologous recombination by platinum-based antitumor agents. 2020 Jun 1
70 32489467 Cytoplasm-localized SIRT1 downregulation attenuates apoptosis and cell cycle arrest in cisplatin-resistant lung cancer A549 cells. 2020 1
71 32512936 A Co-Delivery System of Curcumin and p53 for Enhancing the Sensitivity of Drug-Resistant Ovarian Cancer Cells to Cisplatin. 2020 Jun 4 1
72 32533982 Enhanced expression of lncRNA ZXF1 promotes cisplatin resistance in lung cancer cell via MAPK axis. 2020 Oct 1
73 32630700 The Phytochemical Indicaxanthin Synergistically Enhances Cisplatin-Induced Apoptosis in HeLa Cells via Oxidative Stress-Dependent p53/p21waf1 Axis. 2020 Jul 2 1
74 32641008 Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells. 2020 Jul 8 4
75 32695207 Ginsenoside Rh1 Alleviates HK-2 Apoptosis by Inhibiting ROS and the JNK/p53 Pathways. 2020 1
76 32731241 The Evolving Role of Systemic Therapy in the Primary Treatment of Sinonasal Cancer. 2020 1
77 32738659 Effective treatment of drug-resistant lung cancer via a nanogel capable of reactivating cisplatin and enhancing early apoptosis. 2020 Oct 1
78 32742376 TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents. 2020 Aug 1
79 32818504 Aconitase 2 sensitizes MCF-7 cells to cisplatin eliciting p53-mediated apoptosis in a ROS-dependent manner. 2020 Oct 2
80 32825184 HP1γ Sensitizes Cervical Cancer Cells to Cisplatin through the Suppression of UBE2L3. 2020 Aug 19 4
81 32867831 Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway. 2020 Sep 1 5
82 32881246 Pioglitazone alleviates cisplatin nephrotoxicity by suppressing mitochondria-mediated apoptosis via SIRT1/p53 signalling. 2020 Oct 2
83 32947166 Combined treatment with acetazolamide and cisplatin enhances the chemosensitivity of human head and neck squamous cell carcinoma TU868 cells. 2020 Nov 1
84 32974127 p53 Affects PGC1α Stability Through AKT/GSK-3β to Enhance Cisplatin Sensitivity in Non-Small Cell Lung Cancer. 2020 1
85 33034274 Nipped-B-like Protein Sensitizes Esophageal Squamous Cell Carcinoma Cells to Cisplatin via Upregulation of PUMA. 2020 Jan-Dec 3
86 33040724 Regulation of Thiamine (Vitamin B1)-Dependent Metabolism in Mammals by p53. 2020 Jul 5
87 33086658 The Role of GDF15 in Regulating the Canonical Pathways of the Tumor Microenvironment in Wild-Type p53 Ovarian Tumor and Its Response to Chemotherapy. 2020 Oct 19 2
88 33163850 Germ Cell Tumor Molecular Heterogeneity Revealed Through Analysis of Primary and Metastasis Pairs. 2020 1
89 33174043 Identifying the mechanisms underlying the protective effect of tetramethylpyrazine against cisplatin‑induced in vitro ototoxicity in HEI‑OC1 auditory cells using gene expression profiling. 2020 Dec 1
90 33302475 RNA-Seq Analysis of Cisplatin and the Monofunctional Platinum(II) Complex, Phenanthriplatin, in A549 Non-Small Cell Lung Cancer and IMR90 Lung Fibroblast Cell Lines. 2020 Dec 8 1
91 33396303 Adaptation to Endoplasmic Reticulum Stress Enhances Resistance of Oral Cancer Cells to Cisplatin by Up-Regulating Polymerase η and Increasing DNA Repair Efficiency. 2020 Dec 31 1
92 33520705 TIPE1 Promotes Cervical Cancer Cell Chemoresistance to Cisplatin in a Wild-Type p53-Dependent Manner. 2020 1
93 30144378 ADP sensitizes ZL55 cells to the activity of cisplatin. 2019 Apr 4
94 30445600 TIPE1 promotes cervical cancer progression by repression of p53 acetylation and is associated with poor cervical cancer outcome. 2019 Jun 10 1
95 30447351 N-acetylcysteine ameliorates cisplatin-induced renal senescence and renal interstitial fibrosis through sirtuin1 activation and p53 deacetylation. 2019 Jan 1
96 30478746 The role of p53 status on the synergistic effect of CKD-602 and cisplatin on oral squamous cell carcinoma cell lines. 2019 Feb 1
97 30538112 Identification and Characterization of Synthetic Viability with ERCC1 Deficiency in Response to Interstrand Crosslinks in Lung Cancer. 2019 Apr 15 1
98 30675226 MicroRNA-504 modulates osteosarcoma cell chemoresistance to cisplatin by targeting p53. 2019 Feb 2
99 30690027 Notch1 inhibition enhances DNA damage induced by cisplatin in cervical cancer. 2019 Mar 1 1
100 30723502 Autophagy Regulated by Gain of Function Mutant p53 Enhances Proteasomal Inhibitor-Mediated Cell Death through Induction of ROS and ERK in Lung Cancer Cells. 2019 2