Serine

serpin family C member 1 ; Homo sapiens







32 Article(s)
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1 35062299 Modulation of HIV Replication in Monocyte-Derived Macrophages (MDM) by Host Antiviral Factors Secretory Leukocyte Protease Inhibitor and Serpin Family C Member 1 Induced by Steroid Hormones. 2022 Jan 6 1
2 35563651 The Role of Fibrinolytic System in Health and Disease. 2022 May 9 1
3 35592395 Anticoagulant SERPINs: Endogenous Regulators of Hemostasis and Thrombosis. 2022 1
4 33917853 Investigation of the Differences in Antithrombin to Heparin Binding among Antithrombin Budapest 3, Basel, and Padua Mutations by Biochemical and In Silico Methods. 2021 Apr 8 1
5 34881176 Serpinc1 Acts as a Tumor Suppressor in Hepatocellular Carcinoma Through Inducing Apoptosis and Blocking Macrophage Polarization in an Ubiquitin-Proteasome Manner. 2021 1
6 32422680 Thr90Ser Mutation in Antithrombin is Associated with Recurrent Thrombosis in a Heterozygous Carrier. 2020 Jul 1
7 26797521 The M358R variant of α(1)-proteinase inhibitor inhibits coagulation factor VIIa. 2016 Feb 12 1
8 23578459 [Molecular mechanisms of antithrombin deficiency caused by novel double heterozygous mutations]. 2013 Jan 1 4
9 19689280 Structure-activity relationships of low molecular weight heparins expose to the risk of achieving inappropriate targets in patients with renal failure. 2009 3
10 16940049 Disruption of a tight cluster surrounding tyrosine 131 in the native conformation of antithrombin III activates it for factor Xa inhibition. 2006 Oct 20 2
11 15164384 Molecular basis of inherited antithrombin deficiency in Portuguese families: identification of genetic alterations and screening for additional thrombotic risk factors. 2004 Jun 1
12 12578831 Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol. 2003 Apr 25 1
13 11389017 Autoantibody against prothrombin aberrantly alters the proenzyme to facilitate formation of a complex with its physiological inhibitor antithrombin III without thrombin conversion. 2001 Jun 15 1
14 10660568 Serine 380 (P14) --> glutamate mutation activates antithrombin as an inhibitor of factor Xa. 2000 Feb 11 1
15 10904927 Alpha-1-antitrypsin deficiency, the serpinopathies and conformational disease. 2000 May-Jun 1
16 10064272 Insertion of the Asp-Ser/Phe sequence in the P' position of hirutonin provides molecules having both antithrombin and disintegrin activity. 1999 Feb 15 1
17 9493570 Antithrombin cambridge II (Ala384Ser): clinical, functional and haplotype analysis of 18 families. 1998 Feb 1
18 9521646 Conformational conversion of antithrombin to a fully activated substrate of factor Xa without need for heparin. 1998 Mar 10 1
19 8679610 Mechanism of heparin activation of antithrombin. Evidence for reactive center loop preinsertion with expulsion upon heparin binding. 1996 Jul 2 1
20 7599134 Partial glycosylation of antithrombin III asparagine-135 is caused by the serine in the third position of its N-glycosylation consensus sequence and is responsible for production of the beta-antithrombin III isoform with enhanced heparin affinity. 1995 Jul 4 2
21 7730349 Kinetic characterization of the proteinase binding defect in a reactive site variant of the serpin, antithrombin. Role of the P1' residue in transition-state stabilization of antithrombin-proteinase complex formation. 1995 Apr 28 2
22 7512382 Conformational change in antithrombin induced by heparin probed with a monoclonal antibody against the 1C/4B region. 1994 Apr 12 1
23 8186357 An overview of the mechanism of action of antithrombin and its inherited deficiency states. 1994 Jan 1
24 8205009 Antithrombin and its inherited deficiencies. 1994 Mar 1
25 8392392 General features of the heparin-binding serpins antithrombin, heparin cofactor II and protein C inhibitor. 1993 Jun 2
26 8473344 Dissociation of heparin-dependent thrombin and factor Xa inhibitory activities of antithrombin-III by mutations in the reactive site. 1993 Apr 25 1
27 2160076 Identification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes. 1990 May 2
28 2394749 A retinoic acid-inducible mRNA from F9 teratocarcinoma cells encodes a novel protease inhibitor homologue. 1990 Sep 15 1
29 3260695 Thrombin binding properties of insoluble modified polystyrene: Part II. 1988 Apr 15 2
30 6977539 The active site of antithrombin. Release of the same proteolytically cleaved form of the inhibitor from complexes with factor IXa, factor Xa, and thrombin. 1982 Mar 10 2
31 6790279 Immunological evidence for a proteolytic cleavage at the active site of antithrombin in the mechanism of inhibition of coagulation serine proteases. 1981 Jun 1 1
32 1273513 Acquired thrombophilia: a hitherto unrecognized procoagulant-antithrombin imbalance. 1976 Mar 3