pentasaccharide

serpin family C member 1 ; Homo sapiens







197 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33601159 Structural characterization of fondaparinux interaction with per-6-amino-beta-cyclodextrin: An NMR and MS study. 2021 Apr 15 1
2 31471127 From unfractionated heparin to pentasaccharide: Paradigm of rigorous science growing in the understanding of the in vivo thrombin generation. 2020 Jan 1
3 32515841 Degeneracy of the Antithrombin Binding Sequence in Heparin: 2-O-Sulfated Iduronic Acid Can Replace the Critical Glucuronic Acid. 2020 Sep 10 1
4 29561141 Cooperative Interactions of Three Hotspot Heparin Binding Residues Are Critical for Allosteric Activation of Antithrombin by Heparin. 2018 Apr 17 5
5 29573524 Recognition and Conformational Properties of an Alternative Antithrombin Binding Sequence Obtained by Chemoenzymatic Synthesis. 2018 Mar 24 1
6 28282887 New Insights in Thrombin Inhibition Structure-Activity Relationships by Characterization of Octadecasaccharides from Low Molecular Weight Heparin. 2017 Mar 8 1
7 26672027 Pharmacology of Heparin and Related Drugs. 2016 Jan 1
8 27862941 A century of heparin: past, present and future. 2016 Dec 1
9 26023895 Expression and Characterization of Gly-317 Variants of Factor IX Causing Variable Bleeding in Hemophilia B Patients. 2015 Jun 23 1
10 26059252 Synthesis and Evaluation of a Series of Long-Acting Glucagon-Like Peptide-1 (GLP-1) Pentasaccharide Conjugates for the Treatment of Type 2 Diabetes. 2015 Aug 3
11 26115461 Investigating changes in the gas-phase conformation of Antithrombin III upon binding of Arixtra using traveling wave ion mobility spectrometry (TWIMS). 2015 Oct 21 1
12 26340667 Solution Structure of Heparin Pentasaccharide: NMR and DFT Analysis. 2015 Sep 24 2
13 24354321 Hydroxyl-proton hydrogen bonding in the heparin oligosaccharide Arixtra in aqueous solution. 2014 Jan 16 2
14 24561026 Isolation of a pure octadecasaccharide with antithrombin activity from an ultra-low-molecular-weight heparin. 2014 May 15 3
15 24616065 Affinity capillary electrophoresis for the determination of binding affinities for low molecular weight heparins and antithrombin-III. 2014 May 1
16 24647152 Pharmacological effects and clinical applications of ultra low molecular weight heparins. 2014 Feb 2
17 24735089 Surface modification of polydimethylsiloxane with a covalent antithrombin-heparin complex to prevent thrombosis. 2014 1
18 25145542 Antithrombin-binding oligosaccharides: structural diversities in a unique function? 2014 Oct 1
19 23016581 Antiangiogenic function of antithrombin is dependent on its conformational variation: implication for other serpins. 2013 Apr 2
20 23083208 An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence. 2013 Jan 15 2
21 23843463 Heparin dodecasaccharide containing two antithrombin-binding pentasaccharides: structural features and biological properties. 2013 Sep 6 1
22 23911501 Ultrasonic-assisted preparation of a low molecular weight heparin (LMWH) with anticoagulant activity. 2013 Sep 12 1
23 22315264 Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. 2012 Feb 2
24 22566218 History of heparin. 2012 3
25 23010574 Potentiation of anti-angiogenic activity of heparin by blocking the ATIII-interacting pentasaccharide unit and increasing net anionic charge. 2012 Dec 2
26 23152789 On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different. 2012 1
27 21277398 Immobilization of an antithrombin-heparin complex on gold: anticoagulant properties and platelet interactions. 2011 May 1
28 21297455 Functionality of fondaparinux (pentasaccharide) depends on clinical antithrombin levels. 2011 Apr 1
29 21875153 Energetics of hydrogen bond switch, residue burial and cavity analysis reveals molecular basis of improved heparin binding to antithrombin. 2011 Oct 1
30 19805567 Long-lasting enfuvirtide carrier pentasaccharide conjugates with potent anti-human immunodeficiency virus type 1 activity. 2010 Jan 1
31 19825921 Fondaparinux for the treatment of acute heparin-induced thrombocytopenia: a single-center experience. 2010 Dec 1
32 20816747 Kinetic evidence that allosteric activation of antithrombin by heparin is mediated by two sequential conformational changes. 2010 Dec 15 4
33 21507819 Fondaparinux (Arixtra(R)), a safe alternative for the treatment of patients with heparin-induced thrombocytopenia? 2010 Jun 1
34 19473011 Toward synthesis of the isosteric sulfonate analogues of the AT-III binding domain of heparin. 2009 Jun 18 1
35 19661062 The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation. 2009 Oct 2 6
36 19888512 From heparin to EP217609: the long way to a new pentasaccharide-based neutralisable anticoagulant with an unprecedented pharmacological profile. 2009 Nov 1
37 17909966 Characterization of anticoagulant heparinoids by immunoprofiling. 2008 Feb 1
38 18184032 Fondaparinux: use in thromboprophylaxis of acute medical patients. 2008 1
39 18447601 Idraparinux: review of its clinical efficacy and safety for prevention and treatment of thromboembolic disorders. 2008 May 1
40 18574264 Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). 2008 Jun 2
41 18640975 Antithrombin-binding octasaccharides and role of extensions of the active pentasaccharide sequence in the specificity and strength of interaction. Evidence for very high affinity induced by an unusual glucuronic acid residue. 2008 Sep 26 2
42 18695376 New anticoagulants. 2008 Sep 1
43 19035835 Antiangiogenic forms of antithrombin specifically bind to the anticoagulant heparin sequence. 2008 Dec 23 8
44 17200767 Clot structure modification by fondaparinux and consequence on fibrinolysis: a new mechanism of antithrombotic activity. 2007 Jan 1
45 17229412 Structural view of glycosaminoglycan-protein interactions. 2007 Feb 26 1
46 17323934 High affinity interaction between a synthetic, highly negatively charged pentasaccharide and alpha- or beta-antithrombin is predominantly due to nonionic interactions. 2007 Mar 20 2
47 17536781 Frontal analysis capillary electrophoresis hyphenated to electrospray ionization mass spectrometry for the characterization of the antithrombin/heparin pentasaccharide complex. 2007 Jul 1 4
48 17546440 [Standards and perspectives for thromboembolism prophylaxis]. 2007 Jun 1
49 16475045 New anticoagulants: anti IIa vs anti Xa--is one better? 2006 Feb 1
50 16618121 Pentasaccharide enhances the inactivation of factor Xa by antithrombin by promoting the assembly of a Michaelis-type intermediate complex. Demonstration by rapid kinetic, surface plasmon resonance, and competitive binding studies. 2006 Apr 25 1