| 1 |
34794962 | Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors. | 2022 Feb |
1 |
| 2 |
35068799 | Suppression of Bile Acid Synthesis in a Preterm Infant Receiving Prolonged Parenteral Nutrition. | 2022 Jan-Feb |
2 |
| 3 |
35287950 | MicroRNA-185 modulates CYP7A1 mediated cholesterol-bile acid metabolism through post-transcriptional and post-translational regulation of FoxO1. | 2022 May |
6 |
| 4 |
35397875 | Role of microRNA-185 in the FoxO1-CYP7A1 mediated regulation of bile acid and cholesterol metabolism: A novel target for drug discovery? | 2022 May |
1 |
| 5 |
35526572 | Common Genetic Variants in the Bile Acid Synthesis Enzyme CYP7A1 Are Associated With Severe Primary Bile Acid Diarrhea. | 2022 May 5 |
2 |
| 6 |
35605662 | Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway. | 2022 May 20 |
1 |
| 7 |
33071239 | Leaky Gut and Gut-Liver Axis in Liver Cirrhosis: Clinical Studies Update. | 2021 Sep 15 |
1 |
| 8 |
33484478 | Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function. | 2021 Feb |
1 |
| 9 |
33926590 | Circulating bile acids as a link between the gut microbiota and cardiovascular health: impact of prebiotics, probiotics and polyphenol-rich foods. | 2021 Apr 30 |
1 |
| 10 |
34304130 | Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR. | 2021 Sep |
1 |
| 11 |
34360670 | Fibroblast Growth Factor 21 Response in a Preclinical Alcohol Model of Acute-on-Chronic Liver Injury. | 2021 Jul 23 |
4 |
| 12 |
34552267 | Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling. | 2021 Sep |
2 |
| 13 |
30122083 | Developmental regulation of the gut-liver (FGF19-CYP7A1) axis in neonates. | 2020 Mar |
4 |
| 14 |
32035489 | Ezetimibe promotes CYP7A1 and modulates PPARs as a compensatory mechanism in LDL receptor-deficient hamsters. | 2020 Feb 8 |
1 |
| 15 |
32253466 | Impairment of bile acid metabolism by perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in human HepaRG hepatoma cells. | 2020 May |
1 |
| 16 |
32841642 | Hesperidin alleviates cholestasis via activation of the farnesoid X receptor in vitro and in vivo. | 2020 Oct 15 |
1 |
| 17 |
33132196 | Augmenter of Liver Regeneration (ALR) regulates bile acid synthesis and attenuates bile acid-induced apoptosis via glycogen synthase kinase-3β (GSK-3β) inhibition. | 2020 Dec 1 |
3 |
| 18 |
33414764 | FGF19 and FGF21 for the Treatment of NASH-Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human. | 2020 |
1 |
| 19 |
33692750 | Chenodeoxycholic Acid Modulates Bile Acid Synthesis Independent of Fibroblast Growth Factor 19 in Primary Human Hepatocytes. | 2020 |
1 |
| 20 |
30156739 | CYP7A1 expression in hepatocytes is retained with upregulated fibroblast growth factor 19 in pediatric biliary atresia. | 2019 Mar |
2 |
| 21 |
30414864 | Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial. | 2019 Mar |
1 |
| 22 |
30419252 | Adaptive homeostasis of the vitamin D-vitamin D nuclear receptor axis in 8-methoxypsoralen-induced hepatotoxicity. | 2019 Jan 1 |
1 |
| 23 |
30503707 | Lipoprotein-X fifty years after its original discovery. | 2019 Jan |
1 |
| 24 |
30529590 | Rosuvastatin improves the FGF19 analogue NGM282-associated lipid changes in patients with non-alcoholic steatohepatitis. | 2019 Apr |
1 |
| 25 |
30639138 | Uremic solutes modulate hepatic bile acid handling and induce mitochondrial toxicity. | 2019 Apr |
1 |
| 26 |
30745141 | FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis. | 2019 Feb 25 |
2 |
| 27 |
30978324 | Advances in understanding the regulatory mechanism of cholesterol 7α-hydroxylase. | 2019 Jun |
2 |
| 28 |
31195089 | Bile salts regulate CYP7A1 expression and elicit a fibrotic response and abnormal lipid production in 3D liver microtissues. | 2019 Oct |
1 |
| 29 |
31628911 | Association between the perturbation of bile acid homeostasis and valproic acid-induced hepatotoxicity. | 2019 Dec |
1 |
| 30 |
31661763 | Polyphenol Effects on Cholesterol Metabolism via Bile Acid Biosynthesis, CYP7A1: A Review. | 2019 Oct 28 |
2 |
| 31 |
32153769 | Phytochemicals protect L02 cells against hepatotoxicity induced by emodin via the Nrf2 signaling pathway. | 2019 Nov 1 |
1 |
| 32 |
29529257 | Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease. | 2018 Jun 7 |
2 |
| 33 |
29654817 | Dysregulation of serum bile acids and FGF19 in alcoholic hepatitis. | 2018 Aug |
1 |
| 34 |
29850457 | N-3 Polyunsaturated Fatty Acids Stimulate Bile Acid Detoxification in Human Cell Models. | 2018 |
1 |
| 35 |
30354296 | Interactions Between Regulatory Variants in CYP7A1 (Cholesterol 7α-Hydroxylase) Promoter and Enhancer Regions Regulate CYP7A1 Expression. | 2018 Oct |
2 |
| 36 |
30464886 | Genetic Variations Associated with Anti-Tuberculosis Drug-Induced Liver Injury. | 2018 Jun |
1 |
| 37 |
30504803 | Administration of antibiotics contributes to cholestasis in pediatric patients with intestinal failure via the alteration of FXR signaling. | 2018 Nov 30 |
2 |
| 38 |
27939613 | Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system. | 2017 Mar |
1 |
| 39 |
28302129 | Cholesterol-lowing effect of taurine in HepG2 cell. | 2017 Mar 16 |
1 |
| 40 |
28629595 | A novel intestinal-restricted FXR agonist. | 2017 Aug 1 |
1 |
| 41 |
28805978 | Obeticholic acid, a selective farnesoid X receptor agonist, regulates bile acid homeostasis in sandwich-cultured human hepatocytes. | 2017 Aug |
2 |
| 42 |
29022907 | p38α MAPK antagonizing JNK to control the hepatic fat accumulation in pediatric patients onset intestinal failure. | 2017 Oct 12 |
4 |
| 43 |
26521940 | Hypoxic repression of CYP7A1 through a HIF-1α- and SHP-independent mechanism. | 2016 Mar |
3 |
| 44 |
26606535 | THYROID-STIMULATING HORMONE LEVELS ARE INVERSELY ASSOCIATED WITH SERUM TOTAL BILE ACID LEVELS: A CROSS-SECTIONAL STUDY. | 2016 Apr |
2 |
| 45 |
27052530 | Common Variants in Cholesterol Synthesis- and Transport-Related Genes Associate with Circulating Cholesterol Responses to Intakes of Conventional Dairy Products in Healthy Individuals. | 2016 May |
2 |
| 46 |
27406814 | Non-targeted metabolomics combined with genetic analyses identifies bile acid synthesis and phospholipid metabolism as being associated with incident type 2 diabetes. | 2016 Oct |
1 |
| 47 |
27539104 | The effect of colesevelam treatment on bile acid and lipid metabolism and glycemic control in healthy men. | 2016 Dec 13 |
6 |
| 48 |
27713083 | The antihypercholesterolemic effect of columbamine from Rhizoma Coptidis in HFHC-diet induced hamsters through HNF-4α/FTF-mediated CYP7A1 activation. | 2016 Dec |
1 |
| 49 |
27735997 | Cholesterol-Lowering Effects and Mechanisms in View of Bile Acid Pathway of Resveratrol and Resveratrol Glucuronides. | 2016 Nov |
1 |
| 50 |
28008998 | Impaired Hepatic Adaptation to Chronic Cholestasis induced by Primary Sclerosing Cholangitis. | 2016 Dec 23 |
1 |