pregna-4,17-diene-3,16-dione

xenotropic and polytropic retrovirus receptor 1 ; Homo sapiens







7 Article(s)
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Title
Pub. Year
#Total Relationships
1 31673308 Dissecting the allosteric FXR modulation: a chemical biology approach using guggulsterone as a chemical tool. 2019 Aug 1 1
2 20651339 Guggulsterone suppresses bile acid-induced and constitutive caudal-related homeobox 2 expression in gut-derived adenocarcinoma cells. 2010 Jun 1
3 18980177 Guggulsterone: a potent farnesoid X receptor antagonist and its rapidly evolving role as a systemic anticarcinogenic agent. 2008 Dec 1
4 17135343 The hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: dominance of transactivation over farsenoid X receptor-mediated antagonism. 2007 Mar 1
5 16250653 Is antagonism of E/Z-guggulsterone at the farnesoid X receptor mediated by a noncanonical binding site? A molecular modeling study. 2005 Nov 3 1
6 12525500 Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. 2003 Mar 21 1
7 12705905 Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene. 2003 Apr 25 1