Bile Acids and Salts

xenotropic and polytropic retrovirus receptor 1 ; Homo sapiens







231 Article(s)
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1 33968024 Bile Acids Elevated in Chronic Periaortitis Could Activate Farnesoid-X-Receptor to Suppress IL-6 Production by Macrophages. 2021 1
2 31206730 Direct and Indirect Effects of Fibroblast Growth Factor (FGF) 15 and FGF19 on Liver Fibrosis Development. 2020 Feb 2
3 31630179 Gluco-Metabolic Effects of Pharmacotherapy-Induced Modulation of Bile Acid Physiology. 2020 Jan 1 2
4 31842697 Discovery of selective farnesoid X receptor agonists for the treatment of hyperlipidemia from traditional Chinese medicine based on virtual screening and in vitro validation. 2020 Sep 2
5 31872510 Mechanisms of Parenteral Nutrition-Associated Liver and Gut Injury. 2020 Feb 1
6 32050066 Pose Filter-Based Ensemble Learning Enables Discovery of Orally Active, Nonsteroidal Farnesoid X Receptor Agonists. 2020 Mar 23 1
7 32097559 Computational Insight into the Allosteric Activation Mechanism of Farnesoid X Receptor. 2020 Mar 23 1
8 32112828 A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human Beings. 2020 1
9 30156739 CYP7A1 expression in hepatocytes is retained with upregulated fibroblast growth factor 19 in pediatric biliary atresia. 2019 Mar 1
10 30443932 Interaction of gut microbiota with dysregulation of bile acids in the pathogenesis of nonalcoholic fatty liver disease and potential therapeutic implications of probiotics. 2019 Mar 2
11 30536761 Farnesoid X receptor interacts with cAMP response element binding protein to modulate glucagon-like peptide-1 (7-36) amide secretion by intestinal L cell. 2019 Aug 1
12 30577722 The farnesoid X receptor: a potential target for expanding the therapeutic arsenal against kidney disease. 2019 Feb 2
13 30747230 Bile acids promote gastric intestinal metaplasia by upregulating CDX2 and MUC2 expression via the FXR/NF-κB signalling pathway. 2019 Mar 1
14 30844895 Obeticholic acid in primary biliary cholangitis: where we stand. 2019 May 1
15 30884797 Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties. 2019 Mar 16 2
16 30902657 Farnesoid X receptor agonist GW4064 indirectly inhibits HCV entry into cells via down-regulating scavenger receptor class B type I. 2019 Jun 15 2
17 30910597 Farnesoid X receptor: An important factor in blood glucose regulation. 2019 Aug 2
18 30920307 FXR agonist GW4064 improves liver and intestinal pathology and alters bile acid metabolism in rats undergoing small intestinal resection. 2019 Aug 1 1
19 30967475 Farnesoid X receptor represses matrix metalloproteinase 7 expression, revealing this regulatory axis as a promising therapeutic target in colon cancer. 2019 May 24 1
20 31016648 The C-DILI™ Assay: An Integrated In Vitro Approach to Predict Cholestatic Hepatotoxicity. 2019 4
21 31091123 Bile acid signaling in renal water regulation. 2019 Jul 1 1
22 31106772 [An overview of bile acid synthesis and its physiological and pathological functions]. 2019 May 20 2
23 31161298 Structural Insight into the Binding Mode of FXR and GPBAR1 Modulators. 2019 3
24 31175181 Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters. 2019 Aug 1
25 31201553 Pharmacologic Modulation of Bile Acid-FXR-FGF15/FGF19 Pathway for the Treatment of Nonalcoholic Steatohepatitis. 2019 2
26 31201556 Targeting FXR in Cholestasis. 2019 3
27 31236687 Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic Disease. 2019 1
28 31254667 Semisynthetic bile acids: a new therapeutic option for metabolic syndrome. 2019 Aug 1
29 31267167 Chenodeoxycholic Acid: An Update on Its Therapeutic Applications. 2019 1
30 31341422 Role of Bile Acids in Dysbiosis and Treatment of Nonalcoholic Fatty Liver Disease. 2019 1
31 31853951 Intestinal Absorption of Bile Acids in Health and Disease. 2019 Dec 18 2
32 28709961 Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications. 2018 Apr 1
33 29018272 Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis. 2018 Feb 1
34 29315013 On the Evolution of Bile Salts and the Farnesoid X Receptor in Vertebrates. 2018 Mar/Apr 2
35 29457048 Farnesoid X Receptor Expression in Microscopic Colitis: A Potential Role in Disease Etiopathogenesis. 2018 Jan 1
36 29458053 Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding study. 2018 Jun 1
37 29487110 Farnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and Mechanisms. 2018 May 2
38 29717168 Allosteric modulation of the farnesoid X receptor by a small molecule. 2018 May 1 1
39 29933033 Progress and challenges of selective Farnesoid X Receptor modulation. 2018 Nov 1
40 29958417 Farnesoid X Receptor Activation Enhances Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma Cells. 2018 Jun 28 2
41 30001540 FXR Acts as a Metastasis Suppressor in Intrahepatic Cholangiocarcinoma by Inhibiting IL-6-Induced Epithelial-Mesenchymal Transition. 2018 1
42 30026040 Structural optimization and in vitro profiling of N-phenylbenzamide-based farnesoid X receptor antagonists. 2018 Aug 7 1
43 30259754 FXR modulators for enterohepatic and metabolic diseases. 2018 Nov 1
44 30275017 Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding. 2018 Nov 23 1
45 30453651 Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases. 2018 Nov 17 1
46 30556041 Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na+-Taurocholate Cotransporting Polypeptide. 2018 Dec 2
47 30761355 Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis. 2018 May 28 1
48 28201649 A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR. 2017 Jun 1 1
49 28214524 Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease. 2017 May 1
50 28249261 Crosstalk between Bile Acids and Gut Microbiota and Its Impact on Farnesoid X Receptor Signalling. 2017 4