Arsenic Trioxide

mitogen-activated protein kinase 14 ; Homo sapiens







31 Article(s)
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1 32318339 Inhibition of FEN1 Increases Arsenic Trioxide-Induced ROS Accumulation and Cell Death: Novel Therapeutic Potential for Triple Negative Breast Cancer. 2020 1
2 28241849 Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1. 2017 Feb 28 4
3 26607805 Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells. 2016 Feb 15 2
4 24985180 [The inhibitory effect of As₂O₃ combined with phorbol ester on the proliferation of Kasumi-1 cells and its mechanism]. 2014 Jun 1
5 25130808 [Effects of As2O3 in combination with TPA on K562 cells]. 2014 Aug 1
6 21946058 Arsenic trioxide inhibits Ewing's sarcoma cell invasiveness by targeting p38(MAPK) and c-Jun N-terminal kinase. 2012 Jan 4
7 22293863 MAPK inhibitors and siRNAs differentially affect cell death and ROS levels in arsenic trioxide-treated human pulmonary fibroblast cells. 2012 May 2
8 21741957 Arsenic trioxide and radiation enhance apoptotic effects in HL-60 cells through increased ROS generation and regulation of JNK and p38 MAPK signaling pathways. 2011 Sep 5 1
9 21777978 Arsenic increases lipopolysaccharide-dependent expression of interleukin-8 gene by stimulating a redox-sensitive pathway that strengthens p38-kinase activation. 2011 Sep 3
10 21847655 JWA enhances As₂O₃-induced tubulin polymerization and apoptosis via p38 in HeLa and MCF-7 cells. 2011 Nov 1
11 19608275 Enhanced antimyeloma cytotoxicity by the combination of arsenic trioxide and bortezomib is further potentiated by p38 MAPK inhibition. 2010 Jan 1
12 20129490 Arsenic trioxide-mediated antiplatelet activity: pivotal role of the phospholipase C gamma 2-protein kinase C-p38 MAPK cascade. 2010 Feb 1
13 20164150 The expression of p38, ERK1 and Bax proteins has increased during the treatment of newly diagnosed acute promyelocytic leukemia with arsenic trioxide. 2010 Sep 1
14 20454603 Arsenic Trioxide Modulates DNA Synthesis and Apoptosis in Lung Carcinoma Cells. 2010 May 1 1
15 20632473 Arsenic trioxide modulates DNA synthesis and apoptosis in lung carcinoma cells. 2010 May 1
16 19720055 Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases. 2009 Nov 10 2
17 19846917 The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels. 2009 Oct 1
18 18173754 P38 MAPK inhibition enhancing ATO-induced cytotoxicity against multiple myeloma cells. 2008 Jan 8
19 18412143 The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells. 2008 Oct 6
20 18482988 Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase. 2008 Jul 4 6
21 18695917 Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation. 2008 Sep 4
22 17237268 Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells. 2007 Jan 2
23 17673311 Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways. 2007 Nov 2
24 16762916 Activation of the mitogen- and stress-activated kinase 1 by arsenic trioxide. 2006 Aug 11 1
25 16818652 Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses. 2006 Jul 1 2
26 16445569 Inhibition of mitogen-activated protein kinase kinase enhances apoptosis induced by arsenic trioxide in human breast cancer MCF-7 cells. 2005 Dec 1
27 15007384 Dual effects of glutathione-S-transferase pi on As2O3 action in prostate cancer cells: enhancement of growth inhibition and inhibition of apoptosis. 2004 May 13 1
28 12754411 Arsenic trioxide-induced apoptosis is independent of stress-responsive signaling pathways but sensitive to inhibition of inducible nitric oxide synthase in HepG2 cells. 2003 Apr 30 1
29 12239215 Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to arsenic trioxide. 2002 Nov 22 5
30 11454688 Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer. 2001 Jul 15 1
31 10448126 Low levels of arsenic trioxide stimulate proliferative signals in primary vascular cells without activating stress effector pathways. 1999 Aug 15 1