Phenylalanine

proopiomelanocortin ; Homo sapiens







47 Article(s)
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1 32184956 Single Nucleotide Polymorphisms in the Melanocortin His-Phe-Arg-Trp Sequences Decrease Tetrapeptide Potency and Efficacy. 2020 Mar 12 2
2 28579117 Key amino acid residue in Melanocortin-1 receptor (melanocyte α-MSH receptor) for ligand selectivity. 2017 Oct 15 1
3 28714883 NMR Insights into the Structure-Function Relationships in the Binding of Melanocortin Analogues to the MC1R Receptor. 2017 Jul 15 1
4 27434150 Synthesis of Met-enkephalin by solution-phase peptide synthesis methodology utilizing para-toluene sulfonic acid as N-terminal masking of l-methionine amino acid. 2016 Dec 1
5 25315343 A nonradioactive approach to investigate the metabolism of therapeutic peptides by tagging with 127i and using inductively-coupled plasma mass spectrometry analysis. 2015 Jan 1
6 26095376 Analogue of Melanotan II (MTII): A Novel Melanotropin with Superpotent Action on Frog Skin. 2015 1
7 23276279 An unusual conformation of γ-melanocyte-stimulating hormone analogues leads to a selective human melanocortin 1 receptor antagonist for targeting melanoma cells. 2013 Jan 29 1
8 23293326 Bioinactive ACTH causing glucocorticoid deficiency. 2013 Feb 1
9 19743876 Novel binding motif of ACTH analogues at the melanocortin receptors. 2009 Oct 20 1
10 18991196 Neurometabolic effects of ACTH on free amino compounds in opsoclonus-myoclonus syndrome. 2008 Jun 1
11 17348731 On-line synthesis of pseudopeptide library incorporating a benzodiazepinone turn mimic: biological evaluation on MC1 receptors. 2007 Mar-Apr 1
12 17545153 Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling. 2007 Jul 27 1
13 15749695 Mutation of active site residues of insulin-degrading enzyme alters allosteric interactions. 2005 May 6 1
14 15771429 Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and MC3R analogues. 2005 Mar 24 2
15 17252985 [The role of melanocortin peptides in the cardiovascular regulation in haemorrhagic shock]. 2005 2
16 20642005 67Ga-1,4,7,10-Tetraazacyclododecane-N,N’,N’’,N’’’-tetraacetic acid-Gly-Glu-c[Lys-Nlc-Glu-His-d-Phe-Arg-Trp-Gly-Arg-Pro-Val-Asp] 2004 1
17 12590613 Nardilysin cleaves peptides at monobasic sites. 2003 Feb 25 1
18 12904077 Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R. 2003 Aug 14 1
19 11966977 Synthesis and biological evaluation on hMC3, hMC4 and hMC5 receptors of gamma-MSH analogs substituted with L-alanine. 2002 May 2
20 11970735 Effect of synthetic beta-endorphin-like peptide immunorphin on human T lymphocytes. 2002 Mar 1
21 11101306 Molecular determinants of ligand binding to the human melanocortin-4 receptor. 2000 Dec 5 2
22 10816664 alpha-MSH can control the essential cofactor 6-tetrahydrobiopterin in melanogenesis. 1999 Oct 20 1
23 9699465 Studies of conformational isomerism in alpha-melanocyte stimulating hormone by design of cyclic analogues. 1998 Sep 2
24 9741827 Elevated proenkephalin-derived peptide levels in ACTH-producing adenomas: nucleus and cytoplasm localization. 1998 Jun 2
25 9845266 Melanocortins and cardiovascular regulation. 1998 Oct 30 1
26 18406692 Melanocortins and their implication in melanoma. 1995 May-Jun 1
27 1922962 Correlation between cerebrospinal fluid phenylalanine and beta-endorphin in patients with phenylketonuria. 1991 Aug 5 1
28 2177734 Synthesis of alpha-MSH fragments containing phenylalanine mustard for receptor studies. 1990 Sep 1
29 3031217 Calcium-dependent release of tyrosine in brain elicited by stimulation of neuropeptide receptors. 1987 May 2
30 3116411 The binding of opioid peptides to the Mcg light chain dimer: flexible keys and adjustable locks. 1987 Sep 1
31 3019952 The synthesis of the neuropeptide Met-enkephalin and two metabolic fragments labelled with 11C in the methionine methyl group. 1986 1
32 20493060 Immunohistochemical and biochemical evidence for the presence of the pentapeptide met-enkephalin and the heptapeptide met-enkephalin-Arg(6)-Phe(7) but not the octapeptide met-enkephalin-Arg(6)-Gly(7)-Leu(8) in amphibian chromaffin cells. 1986 5
33 6203623 Serotonin binding sites. I. Structures of sites on myelin basic protein, LHRH, MSH, ACTH, interferon, serum albumin, ovalbumin and red pigment concentrating hormone. 1984 Apr 2
34 6495993 Demonstration and characterization of immunoreactive methionine-enkephalin, leucine-enkephalin, methionine-enkephalin-Arg6-Gly7-Leu8 and methionine-enkephalin-Arg6-Phe7 in human phaeochromocytoma. 1984 Oct 2
35 6526885 Reversed-phase high-performance liquid chromatography studies of alpha-MSH fragments. 1984 Nov 30 1
36 6288599 Human beta-endorphin. 270-MHz 1H-nuclear-magnetic-resonance study of glycyl residues in aqueous solution. 1982 Aug 1
37 7124501 Conversion of Met-enkephalin-Arg-Phe by brain carboxypeptidases and by membrane fractions. 1982 1
38 6261739 Behavioral activity of met-enkephalin and ACTH4-10 and other peptides containing a phenylalanine and methionine residue. 1981 Jan 30 1
39 7440577 The effects of beta-endorphin and enkephalins on protein biosynthesis in a eukaryotic cell-free system. Inhibition of phenylalanyl-tRNA synthetase. 1980 Dec 25 4
40 223580 [Possible consequence of ACTH-like peptides for human mental performance (author's transl)]. 1978 1
41 19605248 Conversion of lipotropic peptides by purified cathepsin D of human pituitary: release of gamma-endorphin by cleavage of the Leu(77)-PHE(78) bond. 1978 Nov 1
42 190838 Biological activities of ACTH-analogues varied in the active site. 1977 Mar 1
43 194605 Changes in muscle action potentials of patients with diseases of motor units following the infusion of a peptide fragment of ACTH. 1977 1
44 844938 Investigation of the role of tryptophan in alpha-MSH. Replacement by L-pentamethylphenylalanine and L-phenylalanine. 1977 1
45 212233 Hormone-receptor interactions. The message sequence of alpha-melanotropin: demonstration of two active sites. 1976 1
46 4375978 Structural studies of alpha-melanocyte-stimulating hormone and a novel beta-melanocyte-stimulating hormone from the neurointermediate lobe of the pituitary of the dogfish Squalus acanthias. 1974 Aug 1
47 14817282 Effect of ACTH and some adrenocortical steroids on the metabolism of tyrosine and phenylalanine in premature infants. 1951 Mar 23 1