Glyburide

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







28 Article(s)
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1 33341937 Hypoglycemia and Glycemic Control With Glyburide in Women With Gestational Diabetes and Genetic Variants of Cytochrome P450 2C9 and/or OATP1B3. 2021 Jul 7
2 32606720 The Effect of CYP2C9 Genotype Variants in Type 2 Diabetes on the Pharmacological Effectiveness of Sulfonylureas, Diabetic Retinopathy, and Nephropathy. 2020 1
3 31086662 Frequency of CYP2C9 (*2, *3 and IVS8-109A>T) allelic variants, and their clinical implications, among Mexican patients with diabetes mellitus type 2 undergoing treatment with glibenclamide and metformin. 2019 May 1
4 29802808 CYP2C9*3 gene variant contributes independently to glycaemic control in patients with type 2 diabetes treated with glibenclamide. 2018 Dec 3
5 30584236 OATP1B3 (699G>A) and CYP2C9*2, *3 significantly influenced the transport and metabolism of glibenclamide and glipizide. 2018 Dec 24 7
6 28522373 Population pharmacokinetics of carvedilol enantiomers and their metabolites in healthy subjects and type-2 diabetes patients. 2017 Nov 15 1
7 27008632 Combined Influence of Genetic Variants and Gene-gene Interaction on Sulfonylurea Efficacy in Type 2 Diabetic Patients. 2016 Mar 1
8 27561267 Evaluation of the pharmacokinetics of glibenclamide tablet given, off label, orally to children suffering from neonatal syndromic hyperglycemia. 2016 Nov 1
9 24839071 Mechanism-based pharmacokinetic modeling to evaluate transporter-enzyme interplay in drug interactions and pharmacogenetics of glyburide. 2014 Jul 1
10 23845193 Severe hypoglycemia due to possible interaction between glibenclamide and sorafenib in a patient with hepatocellular carcinoma. 2013 Apr 2
11 22853867 Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing. 2012 Oct 2
12 21084763 Assessment of the pharmacokinetic interaction between the novel DPP-4 inhibitor linagliptin and a sulfonylurea, glyburide, in healthy subjects. 2011 1
13 21336994 Influence of CYP2C9 gene polymorphisms on response to glibenclamide in type 2 diabetes mellitus patients. 2011 Aug 8
14 20437462 Contributions of human cytochrome P450 enzymes to glyburide metabolism. 2010 May 1
15 20698928 Potential CYP2C9-mediated drug-drug interactions in hospitalized type 2 diabetes mellitus patients treated with the sulphonylureas glibenclamide, glimepiride or glipizide. 2010 Oct 5
16 19515014 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. 2009 1
17 18503607 Sitagliptin, an dipeptidyl peptidase-4 inhibitor, does not alter the pharmacokinetics of the sulphonylurea, glyburide, in healthy subjects. 2008 Jul 1
18 17963417 Pharmacogenetics of glucose-lowering drug treatment: a systematic review. 2007 1
19 16198656 CYP2C9, but not CYP2C19, polymorphisms affect the pharmacokinetics and pharmacodynamics of glyburide in Chinese subjects. 2005 Oct 4
20 16342679 [Impact of cytochrome P450 CYP2C9 variant allele CYP2C9 * 3 on the pharmacokinetics of glibenclamide and lornoxicam in Chinese subjects]. 2005 Sep 6
21 16372821 Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance. 2005 2
22 12920163 Inhibitory effect of glyburide on human cytochrome p450 isoforms in human liver microsomes. 2003 Sep 4
23 11956508 In vivo and in vitro studies exploring the pharmacokinetic interaction between bosentan, a dual endothelin receptor antagonist, and glyburide. 2002 Apr 1
24 11956512 Impact of CYP2C9 amino acid polymorphisms on glyburide kinetics and on the insulin and glucose response in healthy volunteers. 2002 Apr 8
25 12235454 Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes. 2002 Sep 6
26 11368292 Clinical pharmacokinetics of fluvastatin. 2001 2
27 11406737 Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide. 2001 Jun 1
28 11602509 Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9. 2001 Nov 2