Fluvastatin

cytochrome P450 family 2 subfamily C member 9 ; Homo sapiens







42 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33341662 Effects of acid and lactone forms of statins on S-warfarin 7-hydroxylation catalyzed by human liver microsomes and recombinant CYP2C9 variants (CYP2C9.1 and CYP2C9.3). 2021 Feb 1
2 32729746 An updated review of pharmacokinetic drug interactions and pharmacogenetics of statins. 2020 Sep 1
3 30989645 Enantiospecific Pharmacogenomics of Fluvastatin. 2019 Sep 2
4 29368187 Lack of pharmacokinetic interaction between fluvastatin and green tea in healthy volunteers. 2018 May 1
5 30363031 The association between the SLCO1B1, apolipoprotein E, and CYP2C9 genes and lipid response to fluvastatin: a meta-analysis. 2018 Dec 2
6 28674251 Co-administration of Fluvastatin and CYP3A4 and CYP2C8 Inhibitors May Increase the Exposure to Fluvastatin in Carriers of CYP2C9 Genetic Variants. 2017 15
7 26058399 Drug-drug interactions that interfere with statin metabolism. 2015 1
8 24974574 Effect of thyroid hormone status and concomitant medication on statin induced adverse effects in hyperlipidemic patients. 2014 Jun 1
9 25280537 Creatine kinase elevation caused by a combination of fluvastatin and telmisartan in a patient heterozygous for the CYP2C9*3 and ABCC2 -24C > T variants: a case report. 2014 Oct 3 1
10 24024895 CYP2C9 and ABCG2 polymorphisms as risk factors for developing adverse drug reactions in renal transplant patients taking fluvastatin: a case-control study. 2013 Sep 3
11 21820929 [Specific considerations on the prescription and therapeutic interchange of statins]. 2012 Mar-Apr 1
12 22847201 Lipid-lowering effect of fluvastatin in relation to cytochrome P450 2C9 variant alleles frequently distributed in the Czech population. 2012 Aug 6
13 22941809 CYP2C9*3(1075A>C), MDR1 G2677T/A and MDR1 C3435T are determinants of inter-subject variability in fluvastatin pharmacokinetics in healthy Chinese volunteers. 2012 Nov 3
14 22148003 Fatal rhabdomyolysis in a patient with liver cirrhosis after switching from simvastatin to fluvastatin. 2011 Dec 1
15 20178046 Drug interactions with HMG-CoA reductase inhibitors (statins): the importance of CYP enzymes, transporters and pharmacogenetics. 2010 Mar 1
16 20809476 Effect of fluvastatin, lovastatin, nifedipine and verapamil on the systemic exposure of nateglinide in rabbits. 2010 Nov 1
17 19663817 Roles of different CYP enzymes in the formation of specific fluvastatin metabolites by human liver microsomes. 2009 Nov 1
18 17307149 3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design. 2007 Apr 6 1
19 17513950 Effect of HMGCoA reductase inhibitors on cytochrome P450 expression in endothelial cell line. 2007 May 1
20 16388406 Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport. 2006 Mar 1
21 16714062 Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions. 2006 Oct 1
22 17178259 Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. 2006 Dec 2
23 15205386 An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates. 2004 Jul 1
24 15350166 Fluvastatin and fluvastatin extended release: a clinical and safety profile. 2004 Sep 1
25 29793229 The CYP2C9 polymorphism: from enzyme kinetics to clinical dose recommendations. 2004 Dec 1
26 12558459 Interactions between cyclosporin and lipid-lowering drugs: implications for organ transplant recipients. 2003 1
27 12573493 Cytochrome P450 epoxygenases and vascular tone: novel role for HMG-CoA reductase inhibitors in the regulation of CYP 2C expression. 2003 Feb 17 1
28 12822205 [Drug interactions with antilipemics]. 2003 Jan-Feb 1
29 12891229 Influence of CYP2C9 polymorphisms on the pharmacokinetics and cholesterol-lowering activity of (-)-3S,5R-fluvastatin and (+)-3R,5S-fluvastatin in healthy volunteers. 2003 Aug 3
30 14558433 Pharmacological comparison of the statins. 2003 1
31 12036392 Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. 2002 1
32 12044584 Pharmacological interactions of statins. 2002 May 1
33 11368292 Clinical pharmacokinetics of fluvastatin. 2001 3
34 11475198 [Metabolic interactions with statins]. 2001 Jan 20 1
35 10952477 Effect of fluconazole on plasma fluvastatin and pravastatin concentrations. 2000 Jun 3
36 11029845 HMG-CoA reductase inhibitors: assessing differences in drug interactions and safety profiles. 2000 Sep-Oct 1
37 10064574 The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor fluvastatin: effect on human cytochrome P-450 and implications for metabolic drug interactions. 1999 Mar 4
38 10197301 The effects of fluvastatin, a CYP2C9 inhibitor, on losartan pharmacokinetics in healthy volunteers. 1999 Apr 1
39 10665838 New insights into the pharmacodynamic and pharmacokinetic properties of statins. 1999 Dec 1
40 9804052 Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar? 1998 Oct 1
41 8737761 In vitro comparative inhibition profiles of major human drug metabolising cytochrome P450 isozymes (CYP2C9, CYP2D6 and CYP3A4) by HMG-CoA reductase inhibitors. 1996 1
42 7586933 In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (+/-)-fluvastatin. 1995 Oct 2