Dinoprostone

prostaglandin E synthase ; Homo sapiens







109 Article(s)
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1 34465013 Upregulation of prostaglandin E2 by inducible microsomal prostaglandin E synthase-1 in colon cancer. 2022 Apr 2
2 35417776 Sinomenine increases the methylation level at specific GCG site in mPGES-1 promoter to facilitate its specific inhibitory effect on mPGES-1. 2022 Apr 1
3 33053444 Prostaglandin E receptors as targets for ischemic stroke: Novel evidence and molecular mechanisms of efficacy. 2021 Jan 2
4 33441600 Mechanism of action and potential applications of selective inhibition of microsomal prostaglandin E synthase-1-mediated PGE2 biosynthesis by sonlicromanol's metabolite KH176m. 2021 Jan 13 1
5 33494773 Targeted eicosanoids profiling reveals a prostaglandin reprogramming in breast Cancer by microRNA-155. 2021 Jan 25 1
6 33527033 Targeting microsomal prostaglandin E synthase 1 to develop drugs treating the inflammatory diseases. 2021 2
7 34084773 Enhanced mPGES-1 Contributes to PD-Related Peritoneal Fibrosis via Activation of the NLRP3 Inflammasome. 2021 2
8 34405222 [Research advances of prostaglandin E2 synthases and receptors in cardiovascular diseases]. 2021 Aug 25 1
9 32231562 Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells. 2020 2
10 32583353 What about COVID-19 and arachidonic acid pathway? 2020 Nov 1
11 32655834 miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells. 2020 Jun 30 2
12 32926636 Cellular Microenvironment Stiffness Regulates Eicosanoid Production and Signaling Pathways. 2020 Dec 2
13 33028694 2,5-dimethylcelecoxib improves immune microenvironment of hepatocellular carcinoma by promoting ubiquitination of HBx-induced PD-L1. 2020 Oct 1
14 33473256 miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells. 2020 Dec 22 2
15 30814036 MPGES-1 derived PGE2 inhibits cell migration by regulating ARP2/3 in the pathogenesis of Hirschsprung disease. 2019 Oct 5
16 30894570 Inhibition of PGE2/EP4 receptor signaling enhances oxaliplatin efficacy in resistant colon cancer cells through modulation of oxidative stress. 2019 Mar 20 1
17 30897501 Downregulation of microsomal prostaglandin E synthase-1 (mPGES-1) expression in chondrocytes is regulated by MAP kinase phosphatase-1 (MKP-1). 2019 Jun 1
18 31231223 Inhibition of mPGES-1 or COX-2 Results in Different Proteomic and Lipidomic Profiles in A549 Lung Cancer Cells. 2019 2
19 31285948 Stabilization of PTGES by deubiquitinase USP9X promotes metastatic features of lung cancer via PGE2 signaling. 2019 6
20 31320508 IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain. 2019 Jul 19 1
21 31562624 Targeting the COX/mPGES-1/PGE2 Pathway in Neuroblastoma. 2019 1
22 29226424 Activation of EP2 receptor suppresses poly(I: C) and LPS-mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role for MAPKs. 2018 Apr 1
23 29273868 Involvement of TLR3-Dependent PGES Expression in Immunosuppression by Human Bone Marrow Mesenchymal Stem Cells. 2018 Apr 3
24 29597170 Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7. 2018 Apr 25 1
25 29763932 Microvesicles from Human Adipose Tissue-Derived Mesenchymal Stem Cells as a New Protective Strategy in Osteoarthritic Chondrocytes. 2018 1
26 29804818 Inhibition of Microsomal Prostaglandin E Synthase-1 in Cancer-Associated Fibroblasts Suppresses Neuroblastoma Tumor Growth. 2018 Jun 1
27 29891646 mPGES-1 (Microsomal Prostaglandin E Synthase-1) Mediates Vascular Dysfunction in Hypertension Through Oxidative Stress. 2018 Aug 2
28 27611488 Identification of Four Novel Loci in Asthma in European American and African American Populations. 2017 Feb 15 2
29 28458341 The Role of mPGES-1 in Inflammatory Brain Diseases. 2017 1
30 28628921 Activation of COX-2/mPGES-1/PGE2 Cascade via NLRP3 Inflammasome Contributes to Albumin-Induced Proximal Tubule Cell Injury. 2017 1
31 28842681 Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype. 2017 Aug 25 1
32 28854439 mPGES-1-Derived PGE2 Contributes to Indoxyl Sulfate-Induced Mesangial Cell Proliferation. 2017 2
33 28954232 Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E2. 2017 Sep 26 1
34 26791385 Design and Development of Microsomal Prostaglandin E2 Synthase-1 Inhibitors: Challenges and Future Directions. 2016 Jul 14 1
35 27012893 Insights into the structure activity relationship of mPGES-1 inhibitors: Hints for better inhibitor design. 2016 Jul 1
36 27033056 Misoprostol Reverse Hippocampal Neuron Cyclooxygenase-2 Downstream Signaling Imbalance in Aluminum-Overload Rats. 2016 1
37 27159620 Microsomal Prostaglandin E Synthase-1 Expression by Aortic Smooth Muscle Cells Attenuates the Differentiated Phenotype. 2016 Aug 1
38 25314295 Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes. 2015 2
39 25817443 Instability of a dinucleotide repeat in the 3'-untranslated region (UTR) of the microsomal prostaglandin E synthase-1 (mPGES-1) gene in microsatellite instability-high (MSI-H) colorectal carcinoma. 2015 Aug 2
40 25905589 Age-Associated Increase in Skin Fibroblast-Derived Prostaglandin E2 Contributes to Reduced Collagen Levels in Elderly Human Skin. 2015 Sep 2
41 25961169 Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics. 2015 Jun 11 2
42 26123522 Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders. 2015 Nov 1 1
43 26150361 Role of microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 in colon carcinogenesis. 2015 Sep 1
44 26195278 Low-grade inflammation in symptomatic knee osteoarthritis: prognostic value of inflammatory plasma lipids and peripheral blood leukocyte biomarkers. 2015 Nov 1
45 24138533 Characterization of microsomal prostaglandin E synthase 1 inhibitors. 2014 Jan 1
46 24852575 Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS. 2014 2
47 24886859 Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes. 2014 May 16 1
48 25108236 15d-PGJ₂ decreases PGE₂ synthesis in HBx-positive liver cells by interfering EGR1 binding to mPGES-1 promoter. 2014 Oct 1 1
49 23439561 NADPH oxidase NOX5-S and nuclear factor κB1 mediate acid-induced microsomal prostaglandin E synthase-1 expression in Barrett's esophageal adenocarcinoma cells. 2013 May 2
50 23447581 Inhibition of microsomal prostaglandin E synthase-1 by aminothiazoles decreases prostaglandin E2 synthesis in vitro and ameliorates experimental periodontitis in vivo. 2013 Jun 3