Copper

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cytochrome c oxidase copper chaperone COX17 ; Homo sapiens







45 Article(s)
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1 34911956 Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis. 2021 Dec 15 1
2 32416059 Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal. 2020 Jun 4 2
3 30317392 The nonsense-mediated mRNA decay (NMD) pathway differentially regulates COX17, COX19 and COX23 mRNAs. 2019 Apr 1
4 31682224 Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome. 2019 Nov 4 1
5 31903891 Stable COX17 Downregulation Leads to Alterations in Mitochondrial Ultrastructure, Decreased Copper Content and Impaired Cytochrome c Oxidase Biogenesis in HEK293 Cells. 2019 5
6 28938148 Intestinal epithelial cell injury induced by copper containing nanoparticles in piglets. 2017 Dec 1
7 27235272 A comparative study on the interactions of human copper chaperone Cox17 with anticancer organoruthenium(II) complexes and cisplatin by mass spectrometry. 2016 Aug 1
8 27539433 Identification of binding sites of cisplatin to human copper chaperone protein Cox17 by high-resolution FT-ICR-MS. 2016 Aug 2
9 25918166 Cox17 Protein Is an Auxiliary Factor Involved in the Control of the Mitochondrial Contact Site and Cristae Organizing System. 2015 Jun 12 1
10 24343031 Changes in copper concentrations affect the protein levels but not the mRNA levels of copper chaperones in human umbilical vein endothelial cells. 2014 Mar 2
11 24473407 Cisplatin binds to human copper chaperone Cox17: the mechanistic implication of drug delivery to mitochondria. 2014 Mar 11 1
12 25451030 Mia40 combines thiol oxidase and disulfide isomerase activity to efficiently catalyze oxidative folding in mitochondria. 2014 Dec 12 1
13 22937827 Redox and reactive oxygen species regulation of mitochondrial cytochrome C oxidase biogenesis. 2013 Dec 1 2
14 23900152 Copper chaperone for superoxide dismutase-1 transfers copper to mitochondria but does not affect cytochrome c oxidase activity. 2013 Sep 4
15 24204604 Disturbance of copper homeostasis is a mechanism for homocysteine-induced vascular endothelial cell injury. 2013 1
16 21816817 Functional role of two interhelical disulfide bonds in human Cox17 protein from a structural perspective. 2011 Sep 30 2
17 20922212 Genome-wide analysis of eukaryotic twin CX9C proteins. 2010 Dec 1
18 19018666 Modulation of redox switches of copper chaperone Cox17 by Zn(II) ions determined by new ESI MS-based approach. 2009 May 2
19 19393246 Knockdown of human COX17 affects assembly and supramolecular organization of cytochrome c oxidase. 2009 Jun 12 3
20 18093982 A structural-dynamical characterization of human Cox17. 2008 Mar 21 7
21 18458339 Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer. 2008 May 13 1
22 18779302 Role of copper transporters in copper homeostasis. 2008 Sep 1
23 19075668 Copper transport systems are involved in multidrug resistance and drug transport. 2008 1
24 17182746 Human Sco1 functional studies and pathological implications of the P174L mutant. 2007 Jan 2 4
25 17208454 Cox17, a copper chaperone for cytochrome c oxidase: expression, purification, and formation of mixed disulphide adducts with thiol reagents. 2007 May 6
26 17237235 characterization of the cytochrome c oxidase assembly factor Cox19 of Saccharomyces cerevisiae. 2007 Apr 6 1
27 17672825 Oxidative switches in functioning of mammalian copper chaperone Cox17. 2007 Nov 15 14
28 16520371 The P174L mutation in human Sco1 severely compromises Cox17-dependent metallation but does not impair copper binding. 2006 May 5 2
29 16631971 Copper trafficking to the mitochondrion and assembly of copper metalloenzymes. 2006 Jul 2
30 15707358 Ortholog search of proteins involved in copper delivery to cytochrome C oxidase and functional analysis of paralogs and gene neighbors by genomic context. 2005 Jan-Feb 1
31 15893662 Folding studies of Cox17 reveal an important interplay of cysteine oxidation and copper binding. 2005 May 2
32 14972329 Human recombinant mutated forms of the mitochondrial COX assembly Sco2 protein differ from wild-type in physical state and copper binding capacity. 2004 Mar 1
33 15199057 Specific copper transfer from the Cox17 metallochaperone to both Sco1 and Cox11 in the assembly of yeast cytochrome C oxidase. 2004 Aug 20 3
34 15229189 Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase. 2004 Sep 1 1
35 12788943 Mutagenesis reveals a specific role for Cox17p in copper transport to cytochrome oxidase. 2003 Aug 15 4
36 12948382 Copper chaperones, intracellular copper trafficking proteins. Function, structure, and mechanism of action. 2003 Aug 2
37 12370308 Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome C oxidase and embryonic development. 2002 Nov 2
38 11170391 The mitochondrial copper metallochaperone Cox17 exists as an oligomeric, polycopper complex. 2001 Jan 23 3
39 11226237 Zinc metallothionein imported into liver mitochondria modulates respiration. 2001 Feb 27 1
40 10954195 Cytochrome c oxidase assembly factors with a thioredoxin fold are conserved among prokaryotes and eukaryotes. 2000 2
41 10982038 Characterization and localization of human COX17, a gene involved in mitochondrial copper transport. 2000 Jul 2
42 11027508 Characterization of human SCO1 and COX17 genes in mitochondrial cytochrome-c-oxidase deficiency. 2000 Sep 24 1
43 11054125 The expression of Cox17p in rodent tissues and cells. 2000 Nov 1
44 10499084 Copper chaperones: function, structure and copper-binding properties. 1999 Apr 1
45 9050918 Isolation of a cDNA encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment. 1997 Mar 2