Retinoids

haptoglobin-related protein ; Homo sapiens







124 Article(s)
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1 32266855 Mixed micelles of TPGS and Soluplus® for co-delivery of paclitaxel and fenretinide: in vitro and in vivo anticancer study. 2020 Sep 1
2 32366203 Fenretinide-polyethylene glycol (PEG) conjugate with improved solubility enhanced cytotoxicity to cancer cell and potent in vivo efficacy. 2020 Oct 1
3 30061204 4-HPR Is an Endoplasmic Reticulum Stress Aggravator and Sensitizes Breast Cancer Cells Resistant to TRAIL/Apo2L. 2018 Aug 1
4 30251395 Cytotoxic activity of difluoromethylornithine compared with fenretinide in neuroblastoma cell lines. 2018 Dec 1
5 28275870 Synthesis of short retinoidal amides related to fenretinide: antioxidant activities and differentiation-inducing ability. 2017 Apr 1
6 28340497 P450 inhibitor ketoconazole increased the intratumor drug levels and antitumor activity of fenretinide in human neuroblastoma xenograft models. 2017 Jul 15 1
7 28429653 Clinical development of fenretinide as an antineoplastic drug: Pharmacology perspectives. 2017 Jun 1
8 27530131 Reactive Oxygen Species Mediates the Synergistic Activity of Fenretinide Combined with the Microtubule Inhibitor ABT-751 against Multidrug-Resistant Recurrent Neuroblastoma Xenografts. 2016 Nov 1
9 25350317 Combining a BCL2 inhibitor with the retinoid derivative fenretinide targets melanoma cells including melanoma initiating cells. 2015 Mar 1
10 26220867 Dynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemia. 2015 Oct 1
11 23052481 Fenretinide sensitizes multidrug-resistant human neuroblastoma cells to antibody-independent and ch14.18-mediated NK cell cytotoxicity. 2013 Apr 1
12 21964808 The impact of retinoic acid treatment on the sensitivity of neuroblastoma cells to fenretinide. 2012 Jan 1
13 22488409 N-(4-hydroxyphenyl)retinamide inhibits breast cancer cell invasion through suppressing NF-KB activation and inhibiting matrix metalloproteinase-9 expression. 2012 Sep 1
14 22500077 Fenretinide (4-HPR): a preventive chance for women at genetic and familial risk? 2012 1
15 22761939 AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells. 2012 3
16 21498721 Phase I trial of fenretinide lym-x-sorb oral powder in adults with solid tumors and lymphomas. 2011 Mar 1
17 21933888 Synergistic activity of fenretinide and the Bcl-2 family protein inhibitor ABT-737 against human neuroblastoma. 2011 Nov 15 1
18 22061047 Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cells. 2011 Nov 7 1
19 20532509 Relationship among pharmacokinetics and pharmacodynamics of fenretinide and plasma retinol reduction in neuroblastoma patients. 2010 Oct 1
20 20628055 Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells. 2010 Sep 17 1
21 20687958 Brg-1 mediates the constitutive and fenretinide-induced expression of SPARC in mammary carcinoma cells via its interaction with transcription factor Sp1. 2010 Aug 5 1
22 20976277 4-oxo-N-(4-hydroxyphenyl)retinamide: two independent ways to kill cancer cells. 2010 Oct 14 4
23 21117610 Fenretinide-associated multilayered retinal hemorrhage in a patient with hairy cell leukemia. 2010 Nov-Dec 1
24 19213559 Anti-angiogenic properties of chemopreventive drugs: fenretinide as a prototype. 2009 1
25 19331667 Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma. 2009 Mar 30 2
26 19421858 Selective apoptosis induction by the cancer chemopreventive agent N-(4-hydroxyphenyl)retinamide is achieved by modulating mitochondrial bioenergetics in premalignant and malignant human prostate epithelial cells. 2009 Jul 1
27 19482076 ROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells. 2009 Sep 1 1
28 19996280 Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity. 2009 Dec 4
29 17955489 p-Dodecylaminophenol derived from the synthetic retinoid, fenretinide: antitumor efficacy in vitro and in vivo against human prostate cancer and mechanism of action. 2008 Feb 1 1
30 18342855 The PERK/eIF2 alpha signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells. 2008 May 1 1
31 18398104 Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation. 2008 Apr 16 1
32 18515102 Design and synthesis of 4-HPR derivatives for rhabdoid tumors. 2008 Jul 1 1
33 18515328 Selected natural and synthetic retinoids impair CCR7- and CXCR4-dependent cell migration in vitro and in vivo. 2008 Sep 1
34 18556204 Design, synthesis of novel peptidomimetic derivatives of 4-HPR for rhabdoid tumors. 2008 Jul 15 1
35 18602901 N-(4-Hydroxyphenyl) retinamide induced both differentiation and apoptosis in human glioblastoma T98G and U87MG cells. 2008 Aug 28 1
36 17112722 Solid phase-assisted synthesis and screening of a small library of N-(4-hydroxyphenyl)retinamide (4-HPR) analogs. 2007 Feb 1 1
37 17213814 Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells. 2007 Jun 7 1
38 16399227 Anticancer effects of fenretinide in human medulloblastoma. 2006 Jan 18 1
39 16520989 Hypoxia-mediated fenretinide (4-HPR) resistance in childhood acute lymphoblastic leukemia cells. 2006 Oct 1
40 16570282 4-HPR modulates gene expression in ovarian cells. 2006 Sep 1 1
41 16671099 Regulation of lipocalin-2 gene by the cancer chemopreventive retinoid 4-HPR. 2006 Oct 1 2
42 16675469 Mechanism of 4-HPR-induced apoptosis in glioma cells: evidences suggesting role of mitochondrial-mediated pathway and endoplasmic reticulum stress. 2006 Oct 1
43 17024972 Cholecalciferol (vitamin D3) and the retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) are synergistic for chemoprevention of prostate cancer. 2006 2
44 15695235 N-(4-Hydroxyphenyl)retinamide is more potent than other phenylretinamides in inhibiting the growth of BRCA1-mutated breast cancer cells. 2005 May 1
45 15756035 Effect of the synthetic retinoid fenretinide on circulating free prostate-specific antigen, insulin-like growth factor-I, and insulin-like growth factor binding protein-3 levels in men with superficial bladder cancer. 2005 Mar 1 1
46 15816545 Action of fenretinide (4-HPR) on ovarian cancer and endothelial cells. 2005 Jan-Feb 1
47 15863264 Retinoids suppress premalignant MCF10AT but not malignant MCF10CA1a breast epithelial cells in vivo. Role of retinoic acid receptor beta2 expression. 2005 May 26 1
48 15907982 In vitro model of normal, immortalized ovarian surface epithelial and ovarian cancer cells for chemoprevention of ovarian cancer. 2005 Aug 1
49 15917187 ROS mediates 4HPR-induced posttranscriptional expression of the Gadd153 gene. 2005 Jun 15 1
50 16077929 Increased level of the p67phox subunit of NADPH oxidase by 4HPR in head and neck squamous carcinoma cells. 2005 Sep 1