2-mercaptopyrazine

Rac family small GTPase 1 ; Homo sapiens







10 Article(s)
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1 34595833 Rac1/pSTAT3 expression: A pharmacodynamic marker panel as a first step toward optimization of thiopurine therapy in inflammatory bowel disease patients. 2022 Feb 3
2 34720526 Biomarkers for gastrointestinal adverse events related to thiopurine therapy. 2021 Oct 14 1
3 27435106 The ATG16L1 risk allele associated with Crohn's disease results in a Rac1-dependent defect in dendritic cell migration that is corrected by thiopurines. 2017 Mar 1
4 28011186 NK cells are biologic and biochemical targets of 6-mercaptopurine in Crohn's disease patients. 2017 Feb 1
5 27189938 Thiopurine Prodrugs Mediate Immunosuppressive Effects by Interfering with Rac1 Protein Function. 2016 Jun 24 1
6 27465973 Rac1 as a Potential Pharmacodynamic Biomarker for Thiopurine Therapy in Inflammatory Bowel Disease. 2016 Oct 7
7 26015807 Molecular insight into thiopurine resistance: transcriptomic signature in lymphoblastoid cell lines. 2015 1
8 24689502 Comprehensive characterization of (S)GTP-binding proteins by orthogonal quantitative (S)GTP-affinity profiling and (S)GTP/GTP competition assays. 2014 May 6 1
9 23669401 Thiopurine effectiveness in patients with Crohn's disease: a study of genetic and clinical predictive factors. 2013 Jul 1
10 21372752 Evidence for a functional genetic polymorphism of the Rho-GTPase Rac1. Implication in azathioprine response? 2011 Jun 3