Tyrosine

Raf-1 proto-oncogene, serine/threonine kinase ; Homo sapiens







46 Article(s)
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1 31352445 Fibroblast Growth Factors: A Controlling Mechanism of Skin Aging. 2019 1
2 28694330 Phosphorylation of the C-Raf N Region Promotes Raf Dimerization. 2017 Oct 1 2
3 25999467 Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding. 2015 Sep 1
4 25211074 The interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferon. 2014 Sep 10 2
5 24061856 A novel noncanonical signaling pathway for the μ-opioid receptor. 2013 Dec 2
6 22544307 PTPIP51 in protein interactions: regulation and in situ interacting partners. 2012 Jul 1
7 15919658 Phospholipase Cgamma-Erk Axis in vascular endothelial growth factor-induced eukaryotic initiation factor 4E phosphorylation and protein synthesis in renal epithelial cells. 2005 Aug 5 1
8 14673957 Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells. 2004 Jan 1 2
9 12446733 The requirement of specific membrane domains for Raf-1 phosphorylation and activation. 2003 Jan 31 6
10 12551923 Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition. 2003 Mar 28 3
11 12952546 Signaling through Raf-1 in the neovasculature and target validation by nanoparticles. 2003 Jul 30 1
12 11733498 Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1. 2002 Feb 8 1
13 11971897 Activation of c-Raf kinase by ultraviolet light. Regulation by retinoids. 2002 Jun 28 1
14 11376654 Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src. 2001 May 18 2
15 10712905 Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak. 2000 Mar 9 1
16 10921922 Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptor. 2000 Oct 27 1
17 10951567 A different function for a critical tryptophan in c-Raf and Hck. 2000 Jul 27 1
18 12903397 [Expression and kinase activity of B-Raf and Raf-1 in leukemia cell lines]. 2000 Dec 1
19 10205168 Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation. 1999 Apr 15 1
20 10334935 Interleukin-17 induces rapid tyrosine phosphorylation and activation of raf-1 kinase in human monocytic progenitor cell line U937. 1999 May 27 1
21 10373531 Tyrosine phosphorylation of the proto-oncoprotein Raf-1 is regulated by Raf-1 itself and the phosphatase Cdc25A. 1999 Jul 9
22 9611096 Calcium-dependent stimulation of mitogen-activated protein kinase activity in A431 cells by low doses of ionizing radiation. 1998 Jun 1
23 9727031 Mitotic Raf-1 is stimulated independently of Ras and is active in the cytoplasm. 1998 Sep 11 1
24 9794231 Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms. 1998 Sep 24 1
25 9844921 Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells. 1998 Dec 1
26 9020159 Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases. 1997 Feb 14 2
27 9022807 Correlation of constitutive activation of raf-1 with morphological transformation and abrogation of tyrosine phosphorylation of distinct sets of proteins in human squamous carcinoma cells. 1997 Jan 1
28 9154822 Inhibition of the Raf-1 kinase by cyclic AMP agonists causes apoptosis of v-abl-transformed cells. 1997 Jun 1
29 9233777 Association of Grb2 with Sos and Ras with Raf-1 upon gamma irradiation of breast cancer cells. 1997 Jul 3 1
30 9285556 Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1. 1997 Aug 28 2
31 9305939 Role of Janus kinase/signal transducer and activator of transcription and mitogen-activated protein kinase cascades in angiotensin II- and platelet-derived growth factor-induced vascular smooth muscle cell proliferation. 1997 Sep 26 1
32 8641187 Reduced phosphorylation of mitogen-activated protein kinase kinase in response to insulin in cells with truncated C-terminal domain of insulin receptor. 1996 Jun 1
33 8662746 A role for Shc, Grb2, and Raf-1 in FcgammaRI signal relay. 1996 Jun 7 4
34 8703041 Activation of mitogen-activated protein (MAP) kinase pathway by pervanadate, a potent inhibitor of tyrosine phosphatases. 1996 Sep 6 1
35 8752275 Activation of Raf by ionizing radiation. 1996 Aug 29 2
36 8876196 The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner. 1996 Oct 15 1
37 7542586 Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. 1995 Jul 3 3
38 7588214 Forskolin inhibits protein kinase C-induced mitogen activated protein kinase activity in MC3T3-E1 osteoblasts. 1995 Nov 1
39 7722458 The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathway. 1995 May 1 1
40 8260649 Protooncogene-encoded protein kinases in interleukin-2 signal transduction. 1993 Oct 1
41 8260651 Transmembrane signaling by the interleukin-2 receptor: progress and conundrums. 1993 Oct 1
42 1504144 Activation of neutrophils by granulocyte-macrophage colony-stimulating factor. 1992 1
43 1639773 Interleukin-2 (IL-2) induces tyrosine kinase-dependent translocation of active raf-1 from the IL-2 receptor into the cytosol. 1992 Aug 5 1
44 1687313 The Raf-1 serine-threonine kinase is a substrate for the p56lck protein tyrosine kinase in human T-cells. 1991 Dec 1
45 1698619 Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product. 1990 Nov 3
46 2475255 Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. 1989 Aug 25 3