Folic Acid

Dihydrofolate reductase ; Escherichia coli







22 Article(s)
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#Total Relationships
1 31058257 NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. 2019 Mar 2
2 29799386 Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in Escherichia coli. 2018 Jul 2
3 26482924 Sequential backbone resonance assignments of the E. coli dihydrofolate reductase Gly67Val mutant: folate complex. 2016 Apr 1
4 26407224 Vacuum-Ultraviolet Circular Dichroism Spectra of Escherichia coli Dihydrofolate Reductase and Its Mutants: Contributions of Phenylalanine and Tyrosine Side Chains and Exciton Coupling of Two Tryptophan Side Chains. 2015 Oct 15 2
5 25453083 Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography. 2014 Dec 23 1
6 18724364 A domino effect in antifolate drug action in Escherichia coli. 2008 Oct 1
7 14717591 Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase. 2004 Jan 20 2
8 15213241 Mass spectrometry on hydrogen/deuterium exchange of dihydrofolate reductase: effects of ligand binding. 2004 Jun 1
9 15609999 Conformational changes in the active site loops of dihydrofolate reductase during the catalytic cycle. 2004 Dec 28 1
10 14500880 Diagnostic chemical shift markers for loop conformation and substrate and cofactor binding in dihydrofolate reductase complexes. 2003 Oct 1
11 11472112 Energetically most likely substrate and active-site protonation sites and pathways in the catalytic mechanism of dihydrofolate reductase. 2001 Apr 18 3
12 11036056 Resistance to methotrexate due to AcrAB-dependent export from Escherichia coli. 2000 Nov 2
13 10063803 Light activates reduction of methotrexate by NADPH in the ternary complex with Escherichia coli dihydrofolate reductase. 1999 Jan 2
14 10341130 Selective injection of magnetization by slow chemical exchange in NMR. 1999 Jun 2
15 9572847 Deletion of a highly motional residue affects formation of the Michaelis complex for Escherichia coli dihydrofolate reductase. 1998 May 5 1
16 9284325 Effects of fluorine substitution on the structure and dynamics of complexes of dihydrofolate reductase (Escherichia coli). 1997 Sep 2
17 8634297 Engineering specificity for folate into dihydrofolate reductase from Escherichia coli. 1996 Feb 6 2
18 7776369 Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution. 1995 May 26 1
19 1426244 13C NMR studies of complexes of Escherichia coli dihydrofolate reductase formed with methotrexate and with folic acid. 1992 Nov 9 1
20 1961697 The electrostatic potential of Escherichia coli dihydrofolate reductase. 1991 2
21 2190985 The presence and distribution of reduced folates in Escherichia coli dihydrofolate reductase mutants. 1990 Jun 15 1
22 7011378 Kinetics of substrate, coenzyme, and inhibitor binding to Escherichia coli dihydrofolate reductase. 1981 Feb 17 1