Clopidogrel

purinergic receptor P2Y, G-protein coupled 12 ; Mus musculus







34 Article(s)
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1 33242353 P2Y12 antagonism results in altered interactions between platelets and regulatory T cells during sepsis. 2021 Jul 2
2 33991548 Activated platelets contribute to the progression of hepatocellular carcinoma by altering the tumor environment. 2021 Jul 15 1
3 34840926 Nucleotides modulate synoviocyte proliferation and osteoclast differentiation in macrophages with potential implications for rheumatoid arthritis. 2021 Dec 1
4 32089086 Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism. 2020 Apr 10 1
5 32256366 P2Y12 Receptor Antagonist Clopidogrel Attenuates Lung Inflammation Triggered by Silica Particles. 2020 1
6 32268786 Clopidogrel Resistance in a Murine Model of Diet-Induced Obesity Is Mediated by the Interleukin-1 Receptor and Overcome With DT-678. 2020 Jun 1
7 30257062 Genetic deletion of ADP-activated P2Y12 receptor ameliorates lithium-induced nephrogenic diabetes insipidus in mice. 2019 Feb 1
8 30778044 P2Y12 regulates microglia activation and excitatory synaptic transmission in spinal lamina II neurons during neuropathic pain in rodents. 2019 Feb 18 1
9 30354213 Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model. 2018 Oct 1
10 28515278 Critical Role of P2Y12 Receptor in Regulation of Th17 Differentiation and Experimental Autoimmune Encephalomyelitis Pathogenesis. 2017 Jul 1 1
11 26612496 P2Y12 antagonist attenuates eosinophilic inflammation and airway hyperresponsiveness in a mouse model of asthma. 2016 Feb 1
12 26755608 Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier. 2016 Jan 26 1
13 27055904 P2Y12 Receptor Modulates Sepsis-Induced Inflammation. 2016 May 1
14 27221710 Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3-induced outside-in signaling and clusterin release. 2016 May 24 1
15 27475285 Inhibition of PAR-4 and P2Y12 receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease. 2016 Jul 15 1
16 27511945 Ticagrelor regulates osteoblast and osteoclast function and promotes bone formation in vivo via an adenosine-dependent mechanism. 2016 Nov 1
17 25627210 Thrombocytopenia impairs host defense during murine Streptococcus pneumoniae pneumonia. 2015 Mar 1
18 25834071 Platelets are relevant mediators of renal injury induced by primary endothelial lesions. 2015 Jun 1 1
19 22588534 A platelet target for venous thrombosis? P2Y1 deletion or antagonism protects mice from vena cava thrombosis. 2012 Aug 1
20 22996695 The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling. 2012 Oct 1
21 20971951 The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy. 2011 Jan 20 1
22 21447613 Thienopyridines, but not elinogrel, result in off-target effects at the vessel wall that contribute to bleeding. 2011 Jul 1
23 21730013 A clopidogrel-insensitive inducible pool of P2Y12 receptors contributes to thrombus formation: inhibition by elinogrel, a direct-acting, reversible P2Y12 antagonist. 2011 Oct 1
24 20230539 Combination of clopidogrel and everolimus dramatically reduced the development of transplant arteriosclerosis in murine aortic allografts. 2010 Sep 1
25 20451958 Enhanced platelet reactivity and thrombosis in Apoe-/- mice exposed to cigarette smoke is attenuated by P2Y12 antagonism. 2010 Oct 1
26 20930120 Roles and interactions among protease-activated receptors and P2ry12 in hemostasis and thrombosis. 2010 Oct 26 1
27 21067313 Antagonism of P2Y₁₂ reduces physiological thromboxane levels. 2010 1
28 16368572 The role of ADP receptors in platelet function. 2006 May 1 1
29 16466948 The platelet P2 receptors in arterial thrombosis. 2006 Mar-Apr 1
30 15816504 P2Y receptor antagonists in thrombosis. 2005 Mar 2
31 15955565 The platelet P2 receptors as molecular targets for old and new antiplatelet drugs. 2005 Nov 1
32 12969982 Platelet ADP receptors contribute to the initiation of intravascular coagulation. 2004 Jan 15 1
33 14529392 ADP receptors--targets for developing antithrombotic agents. 2003 2
34 11413167 Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs. 2001 Jun 1