| 1 |
34813049 | Maralixibat: First Approval. | 2022 Jan |
1 |
| 2 |
33189717 | S-acylation status of bile acid transporter hASBT regulates its function, metabolic stability, membrane expression, and phosphorylation state. | 2021 Feb 1 |
9 |
| 3 |
33359100 | Dissecting the Conformational Dynamics of the Bile Acid Transporter Homologue ASBTNM. | 2021 Feb 19 |
3 |
| 4 |
33630750 | MECHANISMS IN ENDOCRINOLOGY: FXR signalling: a novel target in metabolic diseases. | 2021 May |
2 |
| 5 |
33782042 | Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters. | 2021 Jun |
5 |
| 6 |
34079822 | Substrate Specificities and Inhibition Pattern of the Solute Carrier Family 10 Members NTCP, ASBT and SOAT. | 2021 |
2 |
| 7 |
34181976 | Research progress in the application of bile acid-drug conjugates: A "trojan horse" strategy. | 2021 Sep |
1 |
| 8 |
34638773 | Placental Expression of Bile Acid Transporters in Intrahepatic Cholestasis of Pregnancy. | 2021 Sep 28 |
2 |
| 9 |
31630179 | Gluco-Metabolic Effects of Pharmacotherapy-Induced Modulation of Bile Acid Physiology. | 2020 Jan 1 |
2 |
| 10 |
32071081 | S-acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells. | 2020 Apr 3 |
3 |
| 11 |
32162131 | Efficient SNP editing in haploid human pluripotent stem cells. | 2020 Apr |
1 |
| 12 |
32201314 | Apical sodium-dependent bile acid transporter, drug target for bile acid related diseases and delivery target for prodrugs: Current and future challenges. | 2020 Aug |
3 |
| 13 |
32209977 | Apical Sodium-Dependent Bile Acid Cotransporter, A Novel Transporter of Indocyanine Green, and Its Application in Drug Screening. | 2020 Mar 23 |
1 |
| 14 |
32234329 | Volixibat in adults with non-alcoholic steatohepatitis: 24-week interim analysis from a randomized, phase II study. | 2020 Aug |
3 |
| 15 |
32588824 | [The inhibitors of the apical sodium-dependent bile acid transporter (ASBT) as promising drugs]. | 2020 May |
7 |
| 16 |
32595517 | IBD and Bile Acid Absorption: Focus on Pre-clinical and Clinical Observations. | 2020 |
1 |
| 17 |
32653991 | Ileal bile acid transporter inhibition as an anticholestatic therapeutic target in biliary atresia and other cholestatic disorders. | 2020 Sep |
11 |
| 18 |
32711025 | Bile acid transporter-mediated oral drug delivery. | 2020 Nov 10 |
9 |
| 19 |
32938201 | Metabolic consequences of ileal interruption of the enterohepatic circulation of bile acids. | 2020 Nov 1 |
3 |
| 20 |
30573812 | A novel ASBT inhibitor, IMB17-15, repressed nonalcoholic fatty liver disease development in high-fat diet-fed Syrian golden hamsters. | 2019 Jul |
5 |
| 21 |
30735608 | Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus. | 2019 May |
2 |
| 22 |
31194565 | Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (SLC10A2). | 2019 Aug 5 |
4 |
| 23 |
31571170 | Intestinal Transporter-Associated Drug Absorption and Toxicity. | 2019 |
1 |
| 24 |
31623375 | Mechanism of Dyslipidemia in Obesity-Unique Regulation of Ileal Villus Cell Brush Border Membrane Sodium-Bile Acid Cotransport. | 2019 Oct 3 |
6 |
| 25 |
28898457 | Organic solute transporter-β (SLC51B) deficiency in two brothers with congenital diarrhea and features of cholestasis. | 2018 Aug |
2 |
| 26 |
29198943 | Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers. | 2018 Mar |
2 |
| 27 |
29304731 | Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a randomised placebo-controlled trial. | 2018 Jan 5 |
4 |
| 28 |
29704003 | Pilot study with IBAT inhibitor A4250 for the treatment of cholestatic pruritus in primary biliary cholangitis. | 2018 Apr 27 |
2 |
| 29 |
29927324 | A novel bioluminescence-based method to investigate uptake of bile acids in living cells. | 2018 Oct 1 |
3 |
| 30 |
30129377 | Elobixibat, the first-in-class Ileal Bile Acid Transporter inhibitor, for the treatment of Chronic Idiopathic Constipation. | 2018 Aug |
4 |
| 31 |
30186169 | Ileal Bile Acid Transporter Inhibition for the Treatment of Chronic Constipation, Cholestatic Pruritus, and NASH. | 2018 |
6 |
| 32 |
30204504 | Elobixibat for the treatment of constipation. | 2018 Oct |
1 |
| 33 |
30344125 | Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure. | 2018 Nov |
3 |
| 34 |
30504769 | Genome-wide association meta-analysis yields 20 loci associated with gallstone disease. | 2018 Nov 30 |
1 |
| 35 |
28249258 | Apical Sodium-Dependent Transporter Inhibitors in Primary Biliary Cholangitis and Primary Sclerosing Cholangitis. | 2017 |
1 |
| 36 |
28249269 | Roles of Ileal ASBT and OSTα-OSTβ in Regulating Bile Acid Signaling. | 2017 |
3 |
| 37 |
28249291 | Bile Acid Uptake Transporters as Targets for Therapy. | 2017 |
3 |
| 38 |
28303230 | A novel class of apical sodium--dependent bile salt transporter inhibitors: 1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides. | 2017 Mar |
5 |
| 39 |
28336180 | An important intestinal transporter that regulates the enterohepatic circulation of bile acids and cholesterol homeostasis: The apical sodium-dependent bile acid transporter (SLC10A2/ASBT). | 2017 Oct |
2 |
| 40 |
29979499 | [Advances in studies of ileal apical sodium-dependent bile acid transporter]. | 2017 Feb |
2 |
| 41 |
25855079 | N-glycosylation is essential for ileal ASBT function and protection against proteases. | 2015 Jun 15 |
1 |
| 42 |
26001962 | Na+/Taurocholate Cotransporting Polypeptide and Apical Sodium-Dependent Bile Acid Transporter Are Involved in the Disposition of Perfluoroalkyl Sulfonates in Humans and Rats. | 2015 Aug |
1 |
| 43 |
26086474 | Design, Synthesis, and Therapeutic Evaluation of Poly(acrylic acid)-tetraDOCA Conjugate as a Bile Acid Transporter Inhibitor. | 2015 Aug 19 |
4 |
| 44 |
24196564 | Sodium-dependent bile salt transporters of the SLC10A transporter family: more than solute transporters. | 2014 Jan |
9 |
| 45 |
24317697 | Structural basis of the alternating-access mechanism in a bile acid transporter. | 2014 Jan 23 |
5 |
| 46 |
24328955 | Structural requirements of the human sodium-dependent bile acid transporter (hASBT): role of 3- and 7-OH moieties on binding and translocation of bile acids. | 2014 Feb 3 |
1 |
| 47 |
24498857 | Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2). | 2014 Apr 15 |
3 |
| 48 |
24566561 | Functional transformations of bile acid transporters induced by high-affinity macromolecules. | 2014 Feb 25 |
2 |
| 49 |
25239307 | The lipid flippase heterodimer ATP8B1-CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells. | 2014 Dec |
1 |
| 50 |
23506869 | The solute carrier family 10 (SLC10): beyond bile acid transport. | 2013 Apr-Jun |
1 |