Dipeptides

solute carrier family 15 member 1 ; Homo sapiens







85 Article(s)
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1 35481706 Lysine Dipeptide Enhances Gut Structure and Whole Body Protein Synthesis in Neonatal Piglets with Intestinal Atrophy. 2022 Apr 27 1
2 35546503 Expression, Regulation, and Role of an Oligopeptide Transporter: PEPT1 in Tumors. 2022 1
3 35634396 Effects of Lysine-Lysine Dipeptide on Serum Amino Acid Profiles, Intestinal Morphology, and Microbiome in Suckling Piglets. 2022 1
4 34371711 Rapid and Sensitive Quantification of Intracellular Glycyl-Sarcosine for Semi-High-Throughput Screening for Inhibitors of PEPT-1. 2021 Jul 3 2
5 30302566 Development and validation of a sensitive LC-MS/MS assay for the quantification of anserine in human plasma and urine and its application to pharmacokinetic study. 2019 Jan 1
6 30644743 Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1. 2019 Feb 13 2
7 30833090 Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter. 2019 Mar 2
8 29890854 Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy. 2018 Nov 5
9 28012236 Effects of Lysine deficiency and Lys-Lys dipeptide on cellular apoptosis and amino acids metabolism. 2017 Sep 1
10 26924013 Structural Design of Oligopeptides for Intestinal Transport Model. 2016 Mar 16 2
11 25650381 Generation of enterocyte-like cells with pharmacokinetic functions from human induced pluripotent stem cells using small-molecule compounds. 2015 Apr 1
12 24422538 Combination of amino acid/dipeptide with nitric oxide donating oleanolic acid derivatives as PepT1 targeting antitumor prodrugs. 2014 Feb 13 1
13 24903899 Simultaneous determination of three dipeptides (JBP485, Gly-Sar and JBP923) in the cell lysates by liquid chromatography-tandem mass spectrometry: application to identify the function of the PEPT1 transfected cell. 2014 Dec 1
14 24082128 Peptide transporter DtpA has two alternate conformations, one of which is promoted by inhibitor binding. 2013 Oct 15 1
15 22263689 Synthesis and evaluation of a dipeptide-drug conjugate library as substrates for PEPT1. 2012 Feb 13 1
16 22490229 Species-dependent uptake of glycylsarcosine but not oseltamivir in Pichia pastoris expressing the rat, mouse, and human intestinal peptide transporter PEPT1. 2012 Jul 1
17 21147219 Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. 2011 Feb 7
18 21262302 Uptake, transport and regulation of JBP485 by PEPT1 in vitro and in vivo. 2011 Apr 1
19 21307350 Evidence for two different broad-specificity oligopeptide transporters in intestinal cell line Caco-2 and colonic cell line CCD841. 2011 Jun 1
20 21529830 Differentiating passive from transporter-mediated uptake by PepT1: a comparison and evaluation of four methods. 2011 Sep 2
21 21538757 Transport of free and peptide-bound glycated amino acids: synthesis, transepithelial flux at Caco-2 cell monolayers, and interaction with apical membrane transport proteins. 2011 May 16 1
22 20104847 Transport of the advanced glycation end products alanylpyrraline and pyrralylalanine by the human proton-coupled peptide transporter hPEPT1. 2010 Feb 24 2
23 20307658 Inhibition of oligopeptide transporter suppress growth of human pancreatic cancer cells. 2010 Jun 14 2
24 20880398 The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics. 2010 Oct 1
25 18781650 Peptide derivation of poorly absorbable drug allows intestinal absorption via peptide transporter. 2009 May 1
26 18824524 High-affinity interaction of sartans with H+/peptide transporters. 2009 Jan 1
27 19084598 Interferon-gamma increases expression of the di/tri-peptide transporter, h-PEPT1, and dipeptide transport in cultured human intestinal monolayers. 2009 Mar 1
28 19685173 Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter. 2009 Oct 1
29 18367661 Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2. 2008 Jun 1
30 18389514 Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity. 2008 Jun 1
31 18485005 DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli. 2008 Jul 1
32 18652477 Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability. 2008 Sep-Oct 1
33 17454359 Cysteine scanning of transmembrane domain three of the human dipeptide transporter: implications for substrate transport. 2007 Apr 1
34 16627568 Molecular interactions between dipeptides, drugs and the human intestinal H+ -oligopeptide cotransporter hPEPT1. 2006 Jul 1 2
35 16759105 Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding. 2006 Jun 15 2
36 17487240 hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides. 2006 Dec 1
37 15623827 Alanylglutamine dipeptide and growth hormone maintain PepT1-mediated transport in oxidatively stressed Caco-2 cells. 2005 Jan 2
38 15934785 hPEPT1 affinity and translocation of selected Gln-Sar and Glu-Sar dipeptide derivatives. 2005 May-Jun 4
39 16039984 Mechanism of inhibition of proton: dipeptide co-transport during chronic enteritis in the mammalian small intestine. 2005 Aug 15 3
40 16244752 Conformational and spacial preferences for substrates of PepT1. 2005 Nov 14 1
41 16267577 Probing dipeptide trans/cis stereochemistry using pH control of thiopeptide analogues, and application to the PepT1 transporter. 2005 Nov 21 1
42 14706812 Analysis of the transport properties of side chain modified dipeptides at the mammalian peptide transporter PEPT1. 2004 Jan 3
43 15981923 Comparison of human and monkey peptide transporters: PEPT1 and PEPT2. 2004 May-Jun 1
44 12526824 Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism. 2003 Jan 17 1
45 12538834 Interactions of the dipeptide ester prodrugs of acyclovir with the intestinal oligopeptide transporter: competitive inhibition of glycylsarcosine transport in human intestinal cell line-Caco-2. 2003 Feb 1
46 12587121 Extracellular glucose concentration alters functional activity of the intestinal oligopeptide transporter (PepT-1) in Caco-2 cells. 2003 Mar 1
47 12598410 Inhibition of intestinal dipeptide transport by the neuropeptide VIP is an anti-absorptive effect via the VPAC1 receptor in a human enterocyte-like cell line (Caco-2). 2003 Feb 2
48 12780388 Epidermal growth factor and insulin short-term increase hPepT1-mediated glycylsarcosine uptake in Caco-2 cells. 2003 Jun 1
49 14520683 Comparison of ceftibuten transport across Caco-2 cells and rat jejunum mounted on modified Ussing chambers. 2003 Oct 1
50 14561585 Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease. 2003 Nov 2