Fatty Acids

acyl-CoA synthetase long chain family member 4 ; Homo sapiens







23 Article(s)
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1 34510514 Therapeutic targeting of hepatic ACSL4 ameliorates NASH in mice. 2022 Jan 1
2 35216678 CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4. 2022 Apr 11 1
3 35603967 CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4-Fatty Acid β-Oxidation Pathway. 2022 May 23 3
4 33068124 New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis. 2021 Mar 2
5 33077484 Long-Chain Acyl-CoA Synthetase 4-Mediated Fatty Acid Metabolism Sustains Androgen Receptor Pathway-Independent Prostate Cancer. 2021 Jan 4
6 33340617 ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway. 2021 Apr 1 1
7 34053456 High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma. 2021 May 31 2
8 34331963 FUNDC1 insufficiency sensitizes high fat diet intake-induced cardiac remodeling and contractile anomaly through ACSL4-mediated ferroptosis. 2021 Sep 2
9 30264402 Suppression of ABCD2 dysregulates lipid metabolism via dysregulation of miR-141:ACSL4 in human osteoarthritis. 2018 Oct 1
10 28334272 17β-estradiol-induced ACSL4 protein expression promotes an invasive phenotype in estrogen receptor positive mammary carcinoma cells. 2017 Apr 1 1
11 28431246 Fatty Acids Regulate Germline Sex Determination through ACS-4-Dependent Myristoylation. 2017 Apr 20 1
12 28551825 Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure. 2017 Oct 1
13 25645621 PPARδ activation induces hepatic long-chain acyl-CoA synthetase 4 expression in vivo and in vitro. 2015 May 1
14 25965523 Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death. 2015 Jul 17 1
15 26147000 Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study. 2015 1
16 26636648 ACSL4 promotes prostate cancer growth, invasion and hormonal resistance. 2015 Dec 29 1
17 24201376 Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol. 2014 Feb 2
18 24341743 Microarray analysis provides new insights into the function of apolipoprotein O in HepG2 cell line. 2013 Dec 17 1
19 20360933 Expression of Long-chain Fatty Acyl-CoA Synthetase 4 in Breast and Prostate Cancers Is Associated with Sex Steroid Hormone Receptor Negativity. 2010 Apr 1
20 21085606 Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells. 2010 Nov 11 1
21 18614287 No association between polymorphisms in the FACL4 (fatty acid-CoA ligase 4) gene and nonspecific mental retardation in Qin-Ba mountain region of China. 2008 Aug 22 1
22 15108178 Association of a long-chain fatty acid-CoA ligase 4 gene polymorphism with depression and with enhanced niacin-induced dermal erythema. 2004 May 15 1
23 11889465 FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation. 2002 Apr 1