Nicotinamide Mononucleotide

nicotinamide phosphoribosyltransferase ; Homo sapiens







40 Article(s)
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1 35408818 NAD+ Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy. 2022 Mar 22 3
2 33777213 NAMPT promotes hepatitis B virus replication and liver cancer cell proliferation through the regulation of aerobic glycolysis. 2021 May 1
3 31818629 Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screening. 2020 Jan 1 2
4 31919382 The effect of NAMPT deletion in projection neurons on the function and structure of neuromuscular junction (NMJ) in mice. 2020 Jan 9 4
5 32005247 Targeting the NAD+ salvage pathway suppresses APC mutation-driven colorectal cancer growth and Wnt/β-catenin signaling via increasing Axin level. 2020 Jan 31 1
6 31324777 Boosting NAD+ with a small molecule that activates NAMPT. 2019 Jul 19 4
7 31338216 Targeting NAMPT as a therapeutic strategy against stroke. 2019 Jul 1
8 31993108 Nicotinamide phosphoribosyltransferase contributes to cocaine addiction through sirtuin 1. 2019 4
9 29337590 Novel Mechanism for Nicotinamide Phosphoribosyltransferase Inhibition of TNF-α-mediated Apoptosis in Human Lung Endothelial Cells. 2018 Jul 1
10 28035412 Nicotinamide phosphoribosyltransferase inhibits receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation in vitro. 2017 Feb 2
11 28714034 Inhibition of NAMPT decreases cell growth and enhances susceptibility to oxidative stress. 2017 Sep 2
12 29156703 Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer. 2017 Oct 17 2
13 26586573 The NAD(+) salvage pathway modulates cancer cell viability via p73. 2016 Apr 4
14 27018006 Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis. 2016 Jun 6
15 27711204 Metabolic Response to NAD Depletion across Cell Lines Is Highly Variable. 2016 4
16 25656579 FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells. 2015 Mar 6 2
17 26024774 Apoptosis induced by NAD depletion is inhibited by KN-93 in a CaMKII-independent manner. 2015 Jul 1 1
18 26538317 NAMPT as a Therapeutic Target against Stroke. 2015 Dec 6
19 24389478 Discovery of a novel nicotinamide phosphoribosyl transferase (NAMPT) inhibitor via in silico screening. 2014 2
20 24407162 Visfatin concentrations in children with leukemia before and after stem cell transplantation. 2014 Apr 1
21 23880765 CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells. 2013 Sep 6 1
22 22119381 Anti-proliferation effect of APO866 on C6 glioblastoma cells by inhibiting nicotinamide phosphoribosyltransferase. 2012 Jan 15 2
23 22430142 NAMPT pathway is involved in the FOXO3a-mediated regulation of GADD45A expression. 2012 Apr 20 4
24 21211508 A fluorometric assay for high-throughput screening targeting nicotinamide phosphoribosyltransferase. 2011 May 1 2
25 21298414 Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans. 2011 May 1
26 21327328 Visfatin/PBEF/Nampt induces EMMPRIN and MMP-9 production in macrophages via the NAMPT-MAPK (p38, ERK1/2)-NF-κB signaling pathway. 2011 Apr 6
27 21484571 Nampt and its potential role in inflammation and type 2 diabetes. 2011 4
28 21518975 Pre-B cell colony-enhancing factor (PBEF/Nampt/visfatin) primes neutrophils for augmented respiratory burst activity through partial assembly of the NADPH oxidase. 2011 Jun 1 1
29 21826208 Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma. 2011 4
30 22073309 Visfatin impairs endothelium-dependent relaxation in rat and human mesenteric microvessels through nicotinamide phosphoribosyltransferase activity. 2011 1
31 20085812 A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis. 2010 Jul 2
32 19109034 Nampt: linking NAD biology, metabolism and cancer. 2009 Apr 2
33 19426698 Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo. 2009 May 15 4
34 19727662 Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity. 2009 Nov 6
35 18823127 Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase. 2008 Oct 21 5
36 18945671 Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism. 2008 Dec 12 1
37 17268245 The regulation of nicotinamide adenine dinucleotide biosynthesis by Nampt/PBEF/visfatin in mammals. 2007 Mar 2
38 17565174 Crystallization of human nicotinamide phosphoribosyltransferase. 2007 May 1 2
39 16783373 Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme. 2006 Jul 1
40 16901503 Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866. 2006 Sep 8 3