NAD

sirtuin 2 ; Mus musculus







34 Article(s)
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1 35264567 Restoring nuclear entry of Sirtuin 2 in oligodendrocyte progenitor cells promotes remyelination during ageing. 2022 Mar 9 2
2 33028985 Tanshinone IIA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehydrogenase in macrophages. 2021 Jun 4
3 33754067 NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin. 2021 1
4 34059674 Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice. 2021 May 31 1
5 34155309 SIRT2 promotes murine melanoma progression through natural killer cell inhibition. 2021 Jun 21 1
6 34183378 Silybin Restored CYP3A Expression through the Sirtuin 2/Nuclear Factor κ-B Pathway in Mouse Nonalcoholic Fatty Liver Disease. 2021 Sep 1
7 34506725 Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2. 2021 Nov 3 1
8 31954883 SIRT2 Contributes to the Regulation of Intestinal Cell Proliferation and Differentiation. 2020 2
9 32032542 An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance. 2020 Mar 3 1
10 32063085 AK-1, a Sirt2 inhibitor, alleviates carbon tetrachloride-induced hepatotoxicity in vivo and in vitro. 2020 Jun 2
11 32278117 Depot-specific regulation of NAD+/SIRTs metabolism identified in adipose tissue of mice in response to high-fat diet feeding or calorie restriction. 2020 Jun 2
12 32697192 Host sirtuin 2 as an immunotherapeutic target against tuberculosis. 2020 Jul 22 1
13 32700357 RTN4B-mediated suppression of Sirtuin 2 activity ameliorates β-amyloid pathology and cognitive impairment in Alzheimer's disease mouse model. 2020 Aug 2
14 30761140 Paclitaxel Enhances the Innate Immunity by Promoting NLRP3 Inflammasome Activation in Macrophages. 2019 1
15 31144814 Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the "Selectivity Pocket", Substrate-Binding Site, and NAD+-Binding Site. 2019 Jun 27 3
16 28970254 Silybin inhibits NLRP3 inflammasome assembly through the NAD+/SIRT2 pathway in mice with nonalcoholic fatty liver disease. 2018 Feb 2
17 29145149 SIRT2 decreases atherosclerotic plaque formation in low-density lipoprotein receptor-deficient mice by modulating macrophage polarization. 2018 Jan 1
18 29189472 SIRT2 and Akt mediate NAD+-induced and NADH-induced increases in the intracellular ATP levels of BV2 microglia under basal conditions. 2018 Jan 17 10
19 29440391 SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis. 2018 Apr 6 2
20 29654491 SIRT2 Inhibition Confers Neuroprotection by Downregulation of FOXO3a and MAPK Signaling Pathways in Ischemic Stroke. 2018 Dec 4
21 30102915 High glucose concentration suppresses a SIRT2 regulated pathway that enhances neurite outgrowth in cultured adult sensory neurons. 2018 Nov 2
22 30533032 SIRT2 knockout exacerbates insulin resistance in high fat-fed mice. 2018 1
23 27460777 Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy. 2017 May 20 1
24 27796760 Downregulation of NAD-Dependent Deacetylase SIRT2 Protects Mouse Brain Against Ischemic Stroke. 2017 Nov 1
25 28778545 SIRT2 inhibition reverses anhedonia in the VGLUT1+/- depression model. 2017 Sep 29 1
26 28894448 Sirtuin 2 Deficiency Increases Bacterial Phagocytosis by Macrophages and Protects from Chronic Staphylococcal Infection. 2017 2
27 26001219 Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner. 2016 Jan 1
28 26060246 Regenerative Neurogenesis After Ischemic Stroke Promoted by Nicotinamide Phosphoribosyltransferase-Nicotinamide Adenine Dinucleotide Cascade. 2015 Jul 5
29 26620281 Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity. 2015 Dec 1 1
30 24003916 Macrophages control innate inflammation. 2013 Sep 1
31 23201684 The NAD-dependent deacetylase SIRT2 is required for programmed necrosis. 2012 Dec 13 3
32 21949390 Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling. 2011 Oct 25 2
33 17560549 Resveratrol abolishes resistance to axonal degeneration in slow Wallerian degeneration (WldS) mice: activation of SIRT2, an NAD-dependent tubulin deacetylase. 2007 Aug 3 3
34 17634366 Proteolipid protein is required for transport of sirtuin 2 into CNS myelin. 2007 Jul 18 2