Alcohols

peroxisome proliferator activated receptor alpha ; Mus musculus







31 Article(s)
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1 33157234 DNA methylation of FTO promotes renal inflammation by enhancing m6A of PPAR-α in alcohol-induced kidney injury. 2021 Jan 2
2 33892114 PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase. 2021 Jun 3
3 34265279 PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1. 2021 Oct 1
4 34267188 Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway. 2021 Jul 15 1
5 34390780 Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance. 2021 Oct 4
6 34603062 Alcohol Abstinence Rescues Hepatic Steatosis and Liver Injury via Improving Metabolic Reprogramming in Chronic Alcohol-Fed Mice. 2021 4
7 33013449 Alcohol and Liver Clock Disruption Increase Small Droplet Macrosteatosis, Alter Lipid Metabolism and Clock Gene mRNA Rhythms, and Remodel the Triglyceride Lipidome in Mouse Liver. 2020 1
8 30602573 Elafibranor interrupts adipose dysfunction-mediated gut and liver injury in mice with alcoholic steatohepatitis. 2019 Feb 14 4
9 31119787 Plin3 protects against alcoholic liver injury by facilitating lipid export from the endoplasmic reticulum. 2019 Sep 1
10 31463983 Vitamin D Deficiency Attenuates Acute Alcohol-Induced Hepatic Lipid Accumulation in Mice. 2019 Oct 1
11 28803762 Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPARα-mediated lipogenic gene expression. 2017 Sep 25 1
12 29020055 Danshen protects against early-stage alcoholic liver disease in mice via inducing PPARα activation and subsequent 4-HNE degradation. 2017 1
13 26857541 PPAR Agonists: II. Fenofibrate and Tesaglitazar Alter Behaviors Related to Voluntary Alcohol Consumption. 2016 Mar 2
14 27287961 Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis. 2016 Sep 1
15 25516156 Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. 2015 Jan 1
16 25915743 Effect of multiple binge alcohol on diet-induced liver injury in a mouse model of obesity. 2015 Apr 27 1
17 26410577 Inhibition of cereblon by fenofibrate ameliorates alcoholic liver disease by enhancing AMPK. 2015 Dec 2
18 24658151 Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration. 2014 1
19 24742988 Pharmacological ceramide reduction alleviates alcohol-induced steatosis and hepatomegaly in adiponectin knockout mice. 2014 Jun 1 2
20 24773203 Modulation of fatty acid and bile acid metabolism by peroxisome proliferator-activated receptor α protects against alcoholic liver disease. 2014 Jun 8
21 25036611 PPAR agonists regulate brain gene expression: relationship to their effects on ethanol consumption. 2014 Nov 1
22 23758436 Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice. 2013 Dec 2
23 24140469 Hepatoprotective effect of mulberry water extracts on ethanol-induced liver injury via anti-inflammation and inhibition of lipogenesis in C57BL/6J mice. 2013 Dec 1
24 21749142 UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model. 2011 Sep 2 3
25 21826694 An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice. 2011 Dec 1
26 20540569 Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the Ppara-null mouse. 2010 Aug 6 4
27 19637192 Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. 2009 Oct 1
28 15368442 Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver. 2004 Aug 1
29 15382117 Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage. 2004 Oct 1
30 17060973 Alcohol deranges hepatic lipid metabolism via altered transcriptional regulation. 2004 6
31 11164737 Regulation of peroxisome proliferator activated receptor alpha-mediated pathways in alcohol fed cytochrome P450 2E1 deficient mice. 2001 Feb 1