Ethanol

peroxisome proliferator activated receptor alpha ; Mus musculus







38 Article(s)
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1 35464439 D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease. 2022 1
2 35526488 PPARα agonist WY-14,643 induces the PLA2/COX-2/ACOX1 pathway to enhance peroxisomal lipid metabolism and ameliorate alcoholic fatty liver in mice. 2022 Jul 12 1
3 35526736 Diallyl disulfide ameliorates ethanol-induced liver steatosis and inflammation by maintaining the fatty acid catabolism and regulating the gut-liver axis. 2022 Jun 2
4 33892114 PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase. 2021 Jun 3
5 34116071 Liver-specific Nrf2 deficiency accelerates ethanol-induced lethality and hepatic injury in vivo. 2021 Sep 1 1
6 34265279 PPARα agonist WY-14,643 induces adipose atrophy and fails to blunt chronic ethanol-induced hepatic fat accumulation in mice lacking adipose FGFR1. 2021 Oct 1
7 34267188 Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway. 2021 Jul 15 3
8 32237978 Downregulation of mitogen-activated protein kinases (MAPKs) in chronic ethanol-induced fatty liver. 2020 Jul 2
9 32534989 Roles of peroxisome proliferator-activated receptor α in the pathogenesis of ethanol-induced liver disease. 2020 Aug 25 2
10 30602573 Elafibranor interrupts adipose dysfunction-mediated gut and liver injury in mice with alcoholic steatohepatitis. 2019 Feb 14 1
11 30803859 FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury. 2019 Apr 1
12 29534306 The hepatic BMAL1/AKT/lipogenesis axis protects against alcoholic liver disease in mice via promoting PPARα pathway. 2018 Sep 1
13 26857541 PPAR Agonists: II. Fenofibrate and Tesaglitazar Alter Behaviors Related to Voluntary Alcohol Consumption. 2016 Mar 10
14 26857685 PPAR Agonists: I. Role of Receptor Subunits in Alcohol Consumption in Male and Female Mice. 2016 Mar 2
15 25501545 Increased 4-hydroxynonenal protein adducts in male GSTA4-4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease. 2015 Mar 1 3
16 25516156 Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. 2015 Jan 1
17 24658151 Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration. 2014 1
18 24730561 Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse. 2014 Jun 1
19 24892905 CMZ reversed chronic ethanol-induced disturbance of PPAR-α possibly by suppressing oxidative stress and PGC-1α acetylation, and activating the MAPK and GSK3β pathway. 2014 4
20 24924749 Dysregulation of hepatic zinc transporters in a mouse model of alcoholic liver disease. 2014 Aug 1 2
21 25036611 PPAR agonists regulate brain gene expression: relationship to their effects on ethanol consumption. 2014 Nov 2
22 25162931 Inhibition of cytochrome P4502E1 by chlormethiazole attenuated acute ethanol-induced fatty liver. 2014 Oct 5 2
23 23388073 Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice. 2013 Feb 6 5
24 24113770 Increased plasma corticosterone contributes to the development of alcoholic fatty liver in mice. 2013 Dec 1
25 24124600 Role of an indole-thiazolidine molecule PPAR pan-agonist and COX inhibitor on inflammation and microcirculatory damage in acute gastric lesions. 2013 1
26 21346097 PPARalpha expression protects male mice from high fat-induced nonalcoholic fatty liver. 2011 Apr 1 1
27 22208561 Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice. 2011 Dec 30 6
28 20622452 Yamabushitake mushroom (Hericium erinaceus) improved lipid metabolism in mice fed a high-fat diet. 2010 2
29 20637825 Tectoridin, an isoflavone glycoside from the flower of Pueraria lobata, prevents acute ethanol-induced liver steatosis in mice. 2010 Sep 30 1
30 19236843 Effects of WY-14,643 on the phosphorylation and activation of AMP-dependent protein kinase. 2009 May 1 2
31 19398233 Polyenephosphatidylcholine prevents alcoholic liver disease in PPARalpha-null mice through attenuation of increases in oxidative stress. 2009 Jun 3
32 18393316 Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice. 2008 May 4
33 18703563 Potential relationship between hepatobiliary osteopontin and peroxisome proliferator-activated receptor alpha expression following ethanol-associated hepatic injury in vivo and in vitro. 2008 Nov 3
34 15194557 Recent advances in alcoholic liver disease II. Minireview: molecular mechanisms of alcoholic fatty liver. 2004 Jul 6
35 15382117 Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage. 2004 Oct 2
36 15670663 Molecular mechanisms of alcoholic fatty liver: role of peroxisome proliferator-activated receptor alpha. 2004 Aug 5
37 12791698 Peroxisome proliferator-activated receptor alpha (PPARalpha) agonist treatment reverses PPARalpha dysfunction and abnormalities in hepatic lipid metabolism in ethanol-fed mice. 2003 Jul 25 12
38 11164737 Regulation of peroxisome proliferator activated receptor alpha-mediated pathways in alcohol fed cytochrome P450 2E1 deficient mice. 2001 Feb 6