Fenofibrate

peroxisome proliferator activated receptor alpha ; Mus musculus







243 Article(s)
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1 33772142 PPARα agonist fenofibrate relieves acquired resistance to gefitinib in non-small cell lung cancer by promoting apoptosis via PPARα/AMPK/AKT/FoxO1 pathway. 2022 Jan 1
2 35143937 Metabolomics reveals the role of PPARα in Tripterygium Wilfordii-induced liver injury. 2022 May 10 1
3 35169201 Mice with a deficiency in Peroxisomal Membrane Protein 4 (PXMP4) display mild changes in hepatic lipid metabolism. 2022 Feb 15 1
4 35214116 Fenofibrate Nano-Eyedrops Ameliorate Retinal Blood Flow Dysregulation and Neurovascular Coupling in Type 2 Diabetic Mice. 2022 Feb 9 1
5 35222033 Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression. 2022 2
6 35414769 Disruption of peroxisome proliferator-activated receptor α in hepatocytes protects against acetaminophen-induced liver injury by activating the IL-6/STAT3 pathway. 2022 2
7 33214136 CEPT1-Mediated Phospholipogenesis Regulates Endothelial Cell Function and Ischemia-Induced Angiogenesis Through PPARα. 2021 Feb 3
8 33408297 Effects of fenofibrate and its combination with lovastatin on the expression of genes involved in skeletal muscle atrophy, including FoxO1 and its targets. 2021 1
9 33434562 Targeting Peroxisome Proliferator-Activated Receptor-α (PPAR- α) to reduce paclitaxel-induced peripheral neuropathy. 2021 Mar 2
10 33556377 Fenofibrate protects the neurovascular unit and ameliorates plasma corticosterone levels in pentylenetetrazole-induced kindling seizure in mice. 2021 May 1 1
11 33603777 Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation. 2021 2
12 33714287 Fenofibrate reverses liver fibrosis in cholestatic mice induced by alpha-naphthylisothiocyanate. 2021 Feb 25 2
13 33799938 Fenofibrate Protects against Retinal Dysfunction in a Murine Model of Common Carotid Artery Occlusion-Induced Ocular Ischemia. 2021 Mar 7 1
14 33916086 Fenofibrate Regulates Visceral Obesity and Nonalcoholic Steatohepatitis in Obese Female Ovariectomized C57BL/6J Mice. 2021 Apr 1 5
15 33937269 Enhancing Fatty Acid Catabolism of Macrophages Within Aberrant Breast Cancer Tumor Microenvironment Can Re-establish Antitumor Function. 2021 4
16 33984335 Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy. 2021 Jul 1
17 34052195 Fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, blocks steatosis and alters the inflammatory response in a mouse model of inflammation-dioxin interaction. 2021 Aug 25 2
18 34082742 The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas. 2021 Jun 3 4
19 34244236 PPARα Agonist Fenofibrate Enhances Cancer Vaccine Efficacy. 2021 Sep 1 2
20 34267188 Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway. 2021 Jul 15 3
21 34268320 PPAR-α Agonist Fenofibrate Prevented Diabetic Nephropathy by Inhibiting M1 Macrophages via Improving Endothelial Cell Function in db/db Mice. 2021 2
22 34287090 PPARα agonist fenofibrate attenuates iron-induced liver injury in mice by modulating the Sirt3 and β-catenin signaling. 2021 Sep 1 4
23 34586065 Profiling sensory neuron microenvironment after peripheral and central axon injury reveals key pathways for neural repair. 2021 Sep 29 1
24 34944662 Activation of PPARα by Fenofibrate Attenuates the Effect of Local Heart High Dose Irradiation on the Mouse Cardiac Proteome. 2021 Dec 6 3
25 34964438 Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA. 2021 Dec 29 1
26 35360222 Fenofibrate Increases the Population of Non-Classical Monocytes in Asymptomatic Chagas Disease Patients and Modulates Inflammatory Cytokines in PBMC. 2021 1
27 32092288 Keratocytes promote corneal neovascularization through VEGFr3 induced by PPARα-inhibition. 2020 Apr 4
28 32194894 Fenofibrate-induced mitochondrial dysfunction and metabolic reprogramming reversal: the anti-tumor effects in gastric carcinoma cells mediated by the PPAR pathway. 2020 2
29 32213513 Pathogenic Role of PPARα Downregulation in Corneal Nerve Degeneration and Impaired Corneal Sensitivity in Diabetes. 2020 Jun 1
30 32232349 PPAR-α Agonist Fenofibrate Suppressed the Formation of Ocular Surface Squamous Metaplasia Induced by Topical Benzalkonium Chloride. 2020 Mar 9 4
31 32350271 Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease. 2020 Apr 29 1
32 32661772 NPC1L1 and ABCG5/8 induction explain synergistic fecal cholesterol excretion in ob/ob mice co-treated with PPAR-α and LXR agonists. 2020 Oct 2
33 32892155 Antiepileptic Drug-Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator-Activated Receptor α and Peroxisome Proliferator-Activated Receptor γ Coactivator 1α-Dependent Gene Expression to Increase Blood Triglyceride Levels. 2020 Nov 2
34 32994417 Satellite glial cells promote regenerative growth in sensory neurons. 2020 Sep 29 1
35 33132907 PPARα Ameliorates Doxorubicin-Induced Cardiotoxicity by Reducing Mitochondria-Dependent Apoptosis via Regulating MEOX1. 2020 2
36 33145027 Fenofibrate prevents iron induced activation of canonical Wnt/β-catenin and oxidative stress signaling in the retina. 2020 1
37 33279456 Peroxisome proliferator-activated receptor α as a novel therapeutic target for schizophrenia. 2020 Dec 1
38 33383736 A Fenofibrate Diet Prevents Paclitaxel-Induced Peripheral Neuropathy in Mice. 2020 Dec 29 3
39 33396512 Fenofibrate Reduces the Severity of Neuroretinopathy in a Type 2 Model of Diabetes without Inducing Peroxisome Proliferator-Activated Receptor Alpha-Dependent Retinal Gene Expression. 2020 Dec 31 3
40 33442383 Fenofibrate Inhibits Subretinal Fibrosis Through Suppressing TGF-β-Smad2/3 signaling and Wnt signaling in Neovascular Age-Related Macular Degeneration. 2020 1
41 30183330 Impairment of Fatty Acid Oxidation in Alveolar Epithelial Cells Mediates Acute Lung Injury. 2019 Feb 1
42 30296701 Fenofibrate improves vascular endothelial function and contractility in diabetic mice. 2019 Jan 2
43 30639234 ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis. 2019 Mar 1
44 30760777 Attenuated Lymphatic Proliferation Ameliorates Diabetic Nephropathy and High-Fat Diet-Induced Renal Lipotoxicity. 2019 Feb 13 1
45 30765336 Fenofibrate Rescues Diabetes-Related Impairment of Ischemia-Mediated Angiogenesis by PPARα-Independent Modulation of Thioredoxin-Interacting Protein. 2019 May 3
46 30955840 Stimulation of Peroxisome Proliferator-Activated Receptor-α by N-Palmitoylethanolamine Engages Allopregnanolone Biosynthesis to Modulate Emotional Behavior. 2019 Jun 15 3
47 31004117 Potent and PPARα-independent anti-proliferative action of the hypolipidemic drug fenofibrate in VEGF-dependent angiosarcomas in vitro. 2019 Apr 19 2
48 31016362 Ablation of aryl hydrocarbon receptor promotes angiotensin II-induced cardiac fibrosis through enhanced c-Jun/HIF-1α signaling. 2019 Jun 2
49 31078963 Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential. 2019 Jul 1
50 31100436 Rosa rugosa flavonoids exhibited PPARα agonist-like effects on genetic severe hypertriglyceridemia of mice. 2019 Aug 10 1