Bezafibrate

peroxisome proliferator activated receptor alpha ; Mus musculus







35 Article(s)
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1 32070771 Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice. 2020 Jun 1 2
2 31163124 Effects of PPARs/20-HETE on the renal impairment under diabetic conditions. 2019 Sep 1 1
3 29695963 The Effects of PPAR Stimulation on Cardiac Metabolic Pathways in Barth Syndrome Mice. 2018 4
4 28127304 Bezafibrate Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis. 2017 3
5 28129657 Physiological characterization of a novel PPAR pan agonist, 2-(4-(5,6-methylenedioxybenzo[d]thiazol-2-yl)-2-methylphenoxy)-2-methylpropanoic acid (MHY2013). 2017 Mar 7 1
6 28279226 The PPAR pan-agonist bezafibrate ameliorates cardiomyopathy in a mouse model of Barth syndrome. 2017 Mar 9 2
7 28545573 Peroxisome Proliferators Activated Receptor (PPAR) agonists activate hepatitis B virus replication in vivo. 2017 May 25 1
8 25510248 Metabolomics reveal 1-palmitoyl lysophosphatidylcholine production by peroxisome proliferator-activated receptor α. 2015 Feb 1
9 23681751 Dill seed extract improves abnormalities in lipid metabolism through peroxisome proliferator-activated receptor-α (PPAR-α) activation in diabetic obese mice. 2013 Jul 1
10 23700465 Peroxisome proliferator-activated receptors-alpha and gamma are targets to treat offspring from maternal diet-induced obesity in mice. 2013 2
11 24200804 Long-chain free fatty acid profiling analysis by liquid chromatography-mass spectrometry in mouse treated with peroxisome proliferator-activated receptor α agonist. 2013 2
12 24455763 Activation of peroxisome proliferator-activated receptor-α (PPARα) in proximal intestine improves postprandial lipidemia in obese diabetic KK-Ay mice. 2013 Sep-Oct 1
13 22095692 Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease. 2012 Mar 1 1
14 22982442 Inhibition of NF-κB activation by 4-hydroxynonenal contributes to liver injury in a mouse model of alcoholic liver disease. 2012 Nov 1
15 21324916 Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes. 2011 May 1
16 21687928 Bezafibrate prevents palmitate-induced apoptosis in osteoblastic MC3T3-E1 cells through the NF-κB signaling pathway. 2011 Oct 1
17 21757225 PPARγ activation induces acute PAI-1 gene expression in the liver but not in adipose tissues of diabetic model mice. 2011 Nov 1
18 21846997 Clofibrate relaxes the longitudinal smooth muscle of the mouse distal colon through calcium-mediated desensitisation of contractile machinery. 2011 1
19 20400680 Bezafibrate induces plasminogen activator inhibitor-1 gene expression in a CLOCK-dependent circadian manner. 2010 Jul 2
20 20594415 Effect of bezafibrate on hepatic oxidative stress: comparison between conventional experimental doses and clinically-relevant doses in mice. 2010 1
21 20854792 PPARα deficiency augments a ketogenic diet-induced circadian PAI-1 expression possibly through PPARγ activation in the liver. 2010 Oct 15 1
22 18287953 PPARalpha is involved in photoentrainment of the circadian clock. 2008 Mar 5 2
23 18368030 Renal L-type fatty acid-binding protein mediates the bezafibrate reduction of cisplatin-induced acute kidney injury. 2008 Jun 1
24 18486101 Cholesterol-lowering effect of bezafibrate is independent of peroxisome proliferator-activated receptor activation in mice. 2008 Jul 1 2
25 18703563 Potential relationship between hepatobiliary osteopontin and peroxisome proliferator-activated receptor alpha expression following ethanol-associated hepatic injury in vivo and in vitro. 2008 Nov 1
26 18787029 Bezafibrate, a peroxisome proliferator-activated receptors agonist, decreases body temperature and enhances electroencephalogram delta-oscillation during sleep in mice. 2008 Oct 1
27 18840432 Circadian expression of FGF21 is induced by PPARalpha activation in the mouse liver. 2008 Oct 29 3
28 17190905 Bezafibrate regulates the expression and enzyme activity of 11beta-hydroxysteroid dehydrogenase type 1 in murine adipose tissue and 3T3-L1 adipocytes. 2007 Apr 1
29 16574099 Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet. 2006 Apr 24 2
30 15447978 Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis. 2005 Jan 1
31 14982965 A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose levels and modifies lipoprotein profiles in KK-Ay mice. 2004 Jun 1
32 12713444 The peroxisome-proliferator-activated receptor alpha agonist ciprofibrate severely aggravates hypercholesterolaemia and accelerates the development of atherosclerosis in mice lacking apolipoprotein E. 2003 Aug 1 1
33 12782154 Bezafibrate is a dual ligand for PPARalpha and PPARbeta: studies using null mice. 2003 Jun 10 2
34 11929713 Aromatase-deficient (ArKO) mice are retrieved from severe hepatic steatosis by peroxisome proliferator administration. 2002 Apr 1
35 10909982 Impaired expression of the uncoupling protein-3 gene in skeletal muscle during lactation: fibrates and troglitazone reverse lactation-induced downregulation of the uncoupling protein-3 gene. 2000 Jul 2