Oxysterols

nuclear receptor subfamily 1, group H, member 3 ; Mus musculus







27 Article(s)
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Pub. Year
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1 34981658 Chronic Activation of LXRα Sensitizes Mice to Hepatocellular Carcinoma. 2022 May 2
2 32432943 Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway. 2021 Jul 3
3 33361391 Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment. 2021 Feb 15 2
4 33631213 4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor. 2021 1
5 34281217 Muricholic Acids Promote Resistance to Hypercholesterolemia in Cholesterol-Fed Mice. 2021 Jul 2 1
6 35082691 Expressing the Human Cholesteryl Ester Transfer Protein Minigene Improves Diet-Induced Fatty Liver and Insulin Resistance in Female Mice. 2021 1
7 30471425 Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma. 2019 Feb 2
8 27052460 Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury. 2017 Jan 4
9 28807695 Doxorubicin enhances oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters. 2017 Nov 15 2
10 29130021 Transgenic Overexpression of Steroid Sulfatase Alleviates Cholestasis. 2017 Jun 5
11 24954418 The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha. 2014 Jul 1 2
12 23284090 On the regulatory role of side-chain hydroxylated oxysterols in the brain. Lessons from CYP27A1 transgenic and Cyp27a1(-/-) mice. 2013 Apr 2
13 23362264 Mechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein. 2013 Mar 22 2
14 23665353 Stereo specific platelet inhibition by the natural LXR agonist 22(R)-OH-cholesterol and its fluorescence labelling with preserved bioactivity and chiral handling in macrophages. 2013 Jul 15 2
15 22732306 Cholesterol metabolite, 5-cholesten-3β-25-diol-3-sulfate, promotes hepatic proliferation in mice. 2012 Nov 1
16 21875689 Synthetic LXR agonist inhibits the development of atherosclerosis in New Zealand White rabbits. 2011 Dec 1
17 20044803 Down-regulation of the LXR transcriptome provides the requisite cholesterol levels to proliferating hepatocytes. 2010 Apr 2
18 17189208 Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. 2007 Jan 5
19 17073762 Liver X receptors and cholesterol homoeostasis: spotlight on the adrenal gland. 2006 Dec 1
20 16054077 Diet-dependent cardiovascular lipid metabolism controlled by hepatic LXRalpha. 2005 May 1
21 15292374 Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor. 2004 Oct 1
22 11851872 Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. 2002 Jan 1
23 12449021 LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis. 2002 Apr 1
24 11238557 Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice. 2001 Mar 1
25 11397693 2000 George Lyman Duff Memorial Lecture: atherosclerosis is a liver disease of the heart. 2001 Jun 1
26 10675617 Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbeta. 2000 Feb 8 1
27 11090131 Role of LXRs in control of lipogenesis. 2000 Nov 15 3