alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide

signal transducer and activator of transcription 3 ; Mus musculus







60 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34380908 Krüppel-like factor 7 attenuates hippocampal neuronal injury after traumatic brain injury. 2022 Mar 1
2 34821076 Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting. 2022 Feb 2
3 35062070 Osteoinductive activity of bisdemethoxycurcumin and its synergistic protective effect with human amniotic mesenchymal stem cells against ovariectomy-induced osteoporosis mouse model. 2022 Feb 1
4 35397421 The mechanism of low-dose radiation-induced upregulation of immune checkpoint molecule expression in lung cancer cells. 2022 Jun 11 2
5 35567856 Interleukin-22 exacerbates angiotensin II-induced hypertensive renal injury. 2022 Aug 1
6 33098244 AG490 protects cerebral ischemia/reperfusion injury via inhibiting the JAK2/3 signaling pathway. 2021 Jan 1
7 33309747 Mutant erythropoietin enhances white matter repair via the JAK2/STAT3 and C/EBPβ pathway in middle-aged mice following cerebral ischemia and reperfusion. 2021 Mar 1
8 33619515 Interleukin 35 protects cardiomyocytes following ischemia/reperfusion-induced apoptosis via activation of mitochondrial STAT3. 2021 Mar 26 1
9 33710777 Exercise-induced peptide EIP-22 protect myocardial from ischaemia/reperfusion injury via activating JAK2/STAT3 signalling pathway. 2021 Apr 1
10 33951698 Effect of Inhibition of the JAK2/STAT3 Signaling Pathway on the Th17/IL-17 Axis in Acute Cellular Rejection After Heart Transplantation in Mice. 2021 Apr 7 1
11 34156153 AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke. 2021 Oct 1
12 32319222 The potential function of miR-135b-mediated JAK2/STAT3 signaling pathway during osteoblast differentiation. 2020 Sep 1
13 32539921 Inhibition of JAK2 by AG490 promotes TNF-α-induced apoptosis by inhibiting autophagy in MC3T3-E1 cells. 2020 Jun 1 2
14 32615888 Curcumin attenuates inflammation and cell apoptosis through regulating NF-κB and JAK2/STAT3 signaling pathway against acute kidney injury. 2020 Aug 1
15 32814243 A novel role of FKN/CX3CR1 in promoting osteogenic transformation of VSMCs and atherosclerotic calcification. 2020 Nov 1
16 32818511 Ruxolitinib attenuates intimal hyperplasia via inhibiting JAK2/STAT3 signaling pathway activation induced by PDGF-BB in vascular smooth muscle cells. 2020 Nov 1
17 30574980 Theanine attenuates memory impairments induced by klotho gene depletion in mice. 2019 Jan 22 1
18 30592974 Astrocytic mobilization of glutathione peroxidase-1 contributes to the protective potential against cocaine kindling behaviors in mice via activation of JAK2/STAT3 signaling. 2019 Feb 1 1
19 30593877 Inhibition of Connexin43 hemichannels with Gap19 protects cerebral ischemia/reperfusion injury via the JAK2/STAT3 pathway in mice. 2019 Mar 1
20 30830585 Mechanism of the JAK2/STAT3-CAV-1-NR2B signaling pathway in painful diabetic neuropathy. 2019 Apr 2
21 30909508 Zoledronate Enhances Osteocyte-Mediated Osteoclast Differentiation by IL-6/RANKL Axis. 2019 Mar 22 1
22 31032948 HIF-1α facilitates osteocyte-mediated osteoclastogenesis by activating JAK2/STAT3 pathway in vitro. 2019 Nov 1
23 31250048 Inhibition of JAK2/STAT3 signaling pathway protects mice from the DDP-induced acute kidney injury in lung cancer. 2019 Sep 1
24 31365165 JAK2-STAT3 signaling pathway is involved in rat periapical lesions induced by Enterococcus faecalis. 2019 Oct 1
25 31379980 CXCL16 Induces the Progression of Pulmonary Fibrosis through Promoting the Phosphorylation of STAT3. 2019 3
26 31399192 The protective role of NR4A3 in acute myocardial infarction by suppressing inflammatory responses via JAK2-STAT3/NF-κB pathway. 2019 Oct 1 1
27 31472144 Knockdown of TRIM66 inhibits cell proliferation, migration and invasion in colorectal cancer through JAK2/STAT3 pathway. 2019 Oct 15 1
28 31733648 Astrocytic endothelin-1 overexpression promotes neural progenitor cells proliferation and differentiation into astrocytes via the Jak2/Stat3 pathway after stroke. 2019 Nov 16 1
29 29751177 Activation of the IL-6/JAK2/STAT3 pathway induces plasma cell mastitis in mice. 2018 Oct 1
30 30044759 Inhibition of JAK2/STAT3 signaling suppresses bone marrow stromal cells proliferation and osteogenic differentiation, and impairs bone defect healing. 2018 Oct 25 2
31 27628046 Platelet-derived growth factor BB enhances osteoclast formation and osteoclast precursor cell chemotaxis. 2017 Jul 1
32 28158495 JAK-STAT signalling and the atrial fibrillation promoting fibrotic substrate. 2017 Mar 1 1
33 28977786 Remote Limb Ischaemic Postconditioning Protects Against Myocardial Ischaemia/Reperfusion Injury in Mice: Activation of JAK/STAT3-Mediated Nrf2-Antioxidant Signalling. 2017 2
34 29029396 Activation of cannabinoid receptor type II by AM1241 protects adipose-derived mesenchymal stem cells from oxidative damage and enhances their therapeutic efficacy in myocardial infarction mice via Stat3 activation. 2017 Sep 12 1
35 26526549 JAK2/STAT3 Pathway Mediates Protection of Metallothionein Against Doxorubicin-Induced Cytotoxicity in Mouse Cardiomyocytes. 2016 May 2
36 26850477 Repeated exposure to far infrared ray attenuates acute restraint stress in mice via inhibition of JAK2/STAT3 signaling pathway by induction of glutathione peroxidase-1. 2016 Mar 1
37 25616906 Activation of Nicotinic Receptors Inhibits TNF-α-Induced Production of Pro-inflammatory Mediators Through the JAK2/STAT3 Signaling Pathway in Fibroblast-Like Synoviocytes. 2015 Aug 1
38 25684945 Overexpression of B7-H3 augments anti-apoptosis of colorectal cancer cells by Jak2-STAT3. 2015 Feb 14 1
39 26352378 Spinal IL-33/ST2 Signaling Contributes to Neuropathic Pain via Neuronal CaMKII-CREB and Astroglial JAK2-STAT3 Cascades in Mice. 2015 Nov 1
40 26438799 Leptin/LepRb in the Ventral Tegmental Area Mediates Anxiety-Related Behaviors. 2015 Oct 5 1
41 24445959 NLRC5 mediates cytokine secretion in RAW264.7 macrophages and modulated by the JAK2/STAT3 pathway. 2014 Jun 1
42 24688026 JAK2-STAT3 blockade by AG490 suppresses autoimmune arthritis in mice via reciprocal regulation of regulatory T Cells and Th17 cells. 2014 May 1 2
43 24690200 Hydroxy-safflor yellow A attenuates Aβ₁₋₄₂-induced inflammation by modulating the JAK2/STAT3/NF-κB pathway. 2014 May 14 1
44 23266654 Essential role of JAK/STAT pathway in the induction of cell cycle arrest in macrophages infected with periodontopathic bacterium Aggregatibacter actinomycetemcomitans. 2013 Apr 1
45 23455376 ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice. 2013 Jul 1
46 23511693 Down-regulation of insulin signaling is involved in painful diabetic neuropathy in type 2 diabetes. 2013 Mar-Apr 1
47 21931823 Timing is critical for an effective anti-metastatic immunotherapy: the decisive role of IFNγ/STAT1-mediated activation of autophagy. 2011 1
48 19400741 Nogo-66 regulates nanog expression through stat3 pathway in murine embryonic stem cells. 2010 Jan 1
49 18795895 Adiponectin induces interleukin-6 production and activates STAT3 in adult mouse cardiac fibroblasts. 2009 May 2
50 19416544 Inhibition of zymosan-induced kidney dysfunction by tyrphostin AG-490. 2009 May 5 1