Metformin

signal transducer and activator of transcription 3 ; Mus musculus







22 Article(s)
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Pub. Year
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1 35414608 Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway. 2022 Apr 4
2 33947424 Metformin ameliorates scleroderma via inhibiting Th17 cells and reducing mTOR-STAT3 signaling in skin fibroblasts. 2021 May 4 4
3 34269008 Potential effect of EGCG on the anti-tumor efficacy of metformin in melanoma cells. 2021 Jul 15 1
4 31904843 Metformin enhances the immunomodulatory potential of adipose-derived mesenchymal stem cells through STAT1 in an animal model of lupus. 2020 Jun 1 1
5 32104542 Metformin Reduces the Senescence of Renal Tubular Epithelial Cells in Diabetic Nephropathy via the MBNL1/miR-130a-3p/STAT3 Pathway. 2020 4
6 32646922 Low-Dose Metformin Reprograms the Tumor Immune Microenvironment in Human Esophageal Cancer: Results of a Phase II Clinical Trial. 2020 Sep 15 1
7 30675314 Metformin selectively targets 4T1 tumorspheres and enhances the antitumor effects of doxorubicin by downregulating the AKT and STAT3 signaling pathways. 2019 Feb 1
8 30935688 Metformin alleviates inflammatory response in non-alcoholic steatohepatitis by restraining signal transducer and activator of transcription 3-mediated autophagy inhibition in vitro and in vivo. 2019 May 21 4
9 31250538 Metformin modulates immune cell infiltration into the kidney during unilateral ureteral obstruction in mice. 2019 Aug 2
10 31550676 Metformin inhibits the function of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. 2019 Dec 1
11 29650774 Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes. 2018 Jul 3
12 30206377 Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model. 2018 Sep 11 1
13 28242651 Metformin Suppresses Systemic Autoimmunity in Roquinsan/san Mice through Inhibiting B Cell Differentiation into Plasma Cells via Regulation of AMPK/mTOR/STAT3. 2017 Apr 1 3
14 27145454 Metformin blocks progression of obesity-activated thyroid cancer in a mouse model. 2016 Jun 7 1
15 25370454 Metformin decreases IL-22 secretion to suppress tumor growth in an orthotopic mouse model of hepatocellular carcinoma. 2015 Jun 1 1
16 25552600 Metformin inhibits monocyte-to-macrophage differentiation via AMPK-mediated inhibition of STAT3 activation: potential role in atherosclerosis. 2015 Jun 1
17 25875801 Metformin suppresses pancreatic tumor growth with inhibition of NFκB/STAT3 inflammatory signaling. 2015 May 2
18 26360050 Metformin Ameliorates Inflammatory Bowel Disease by Suppression of the STAT3 Signaling Pathway and Regulation of the between Th17/Treg Balance. 2015 2
19 24789104 Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis. 2014 2
20 24976178 Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained. 2014 Aug 5 1
21 23557965 Metformin downregulates Th17 cells differentiation and attenuates murine autoimmune arthritis. 2013 May 1
22 22349108 Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models. 2012 May 3